Alcuronium (Cl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Alcuronium (Cl) is a competitive or non-depolarizing neuromuscular blocking agent. Alcuronium (Cl) is a synthetic derivative of the curare alkaloid Toxiferine. Alcuronium (Cl) is used to provide muscle relaxation in general anesthesia (loss of consciousness) for surgical procedures.It has an intermediate onset and duration of action.
Indications
Alcuronium (Cl) is primarily indicated in conditions like Adjunct to anesthesia, Neuromuscular blockade.
Contraindications
Alcuronium (Cl) is contraindicated in conditions like Hypersensitivity.
Side Effects
Alcuronium (Cl) produces potentially life-threatening effects which include Anaphylactoid reactions, Hypotension, Cardiac Arrest, Cardiac arrest, Bronchospasm, Bronchospasm. which are responsible for the discontinuation of Alcuronium (Cl) therapy.The signs and symptoms that are produced after the acute overdosage of Alcuronium (Cl) include Prolonged respiratory & muscular paralysis.The symptomatic adverse reactions produced by Alcuronium (Cl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, GI symptoms, Increase in heart rate.
Warnings
Alcuronium should be used with caution in patients with impaired renal function or during pregnancy.
High Risk Groups
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.2 to 0.3 mg/kg (0.25 (0.25)) As recommended. IV — As Required
Child Dosage
0.13 to 0.2 mg/Kg (0.16 (0.165)) As recommended. Intra Venous — As Required
Neonatal Dosage
0.13 to 0.2 mg/Kg (0.16 (0.165)) As recommended. Intra Venous — As Required
Drug Interactions
Alcuronium (Cl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementBendrofluazideEnfluraneHalothaneHydroflumethiazideLignocaineLincomycin (HCl)PenicillaminePhenytoin (Na)Polymyxin B (Sulphate)Procainamide (HCl)QuinidineVerapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
IV Inj Store at room temperature. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.