Alfuzosin

Alfuzosin is used to treat the signs and symptoms of benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems with urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely. Alfuzosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms. However, alfuzosin will not shrink the prostate. The prostate may continue to get larger. This may cause the symptoms to become worse over time. Therefore, even though alfuzosin may lessen the problems caused by enlarged prostate now, surgery may still be needed in the future. This medicine is usually given only to men. It is not normally given to women or children. This medicine is available only with your doctor's prescription.

Alfuzosin is used to treat the signs and symptoms of benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems with urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely. Alfuzosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms. However, alfuzosin will not shrink the prostate. The prostate may continue to get larger. This may cause the symptoms to become worse over time. Therefore, even though alfuzosin may lessen the problems caused by enlarged prostate now, surgery may still be needed in the future. This medicine is usually given only to men. It is not normally given to women or children. This medicine is available only with your doctor's prescription.

Alfuzosin is contraindicated in conditions like Hypotension, Hypersensitivity, Hepatic insufficiency.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare Chest pain chills cold sweats confusion dizziness, faintness, or lightheadedness when getting up from a lying or sitting position fainting fast, pounding, or irregular heartbeat or pulse painful or prolonged erection of the penis Incidence not known Arm, back, or jaw pain black, tarry stools bleeding gums bloody urine chest discomfort, tightness, or heaviness clay-colored stools dark urine diarrhea fever headache hives, welts, itching, skin rash large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals loss of appetite nausea pinpoint red spots on the skin stomach pain sweating swelling unpleasant breath odor unusual bleeding or bruising unusual tiredness or weakness vomiting of blood yellow eyes or skin Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Belching body aches or pain congestion cough cough producing mucus decreased interest in sexual intercourse difficulty breathing difficulty having a bowel movement dryness or soreness of the throat ear congestion heartburn hoarseness inability to have or keep an erection indigestion loss in sexual ability, desire, drive, or performance loss of voice nasal congestion pain pain or tenderness around the eyes and cheekbones sneezing sore throat stomach discomfort or upset stuffy or runny nose tender, swollen glands in the neck tightness in the chest trouble with swallowing unusual tiredness or weakness voice changes Incidence not known Feeling of warmth redness of the face, neck, arms, and occasionally, upper chest Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

To avoid first dose effect i.e. marked postural hypotension and syncope, initial dose should be reduced and to be taken at the bed time.

Drug should not be given to Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

2.5 to 10 mg (6.2 (6.25)) 8 hourly PO —

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Atazanavir Bepridil Boceprevir Cisapride Clarithromycin Cobicistat Conivaptan Darunavir Dronedarone Fluconazole Fosamprenavir Idelalisib Indinavir Itraconazole Ketoconazole Levoketoconazole Lopinavir Mesoridazine Nelfinavir Nirmatrelvir Pimozide Piperaquine Posaconazole Ritonavir Saquinavir Sparfloxacin Telaprevir Telithromycin Terfenadine Thioridazine Tipranavir Ziprasidone Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Abametapir Adagrasib Amiodarone Amisulpride Amitriptyline Amoxapine Anagrelide Apomorphine Aripiprazole Aripiprazole Lauroxil Arsenic Trioxide Asenapine Astemizole Azithromycin Bedaquiline Bunazosin Buprenorphine Buserelin Ceritinib Chloroquine Chlorpromazine Ciprofloxacin Citalopram Clofazimine Clomipramine Clothiapine Clozapine Crizotinib Dabrafenib Dapiprazole Dasatinib Degarelix Delamanid Desipramine Deslorelin Deutetrabenazine Dexmedetomidine Disopyramide Dofetilide Dolasetron Domperidone Donepezil Doxazosin Droperidol Efavirenz Encorafenib Entrectinib Escitalopram Etrasimod Fedratinib Fexinidazole Fingolimod Flecainide Fluoxetine Formoterol Foscarnet Fosnetupitant Fostemsavir Gatifloxacin Gemifloxacin Gepirone Glasdegib Gonadorelin Goserelin Granisetron Halofantrine Haloperidol Histrelin Hydroxychloroquine Hydroxyzine Ibutilide Iloperidone Imipramine Inotuzumab Ozogamicin Ivabradine Ivosidenib Lapatinib Lefamulin Lenvatinib Leuprolide Levofloxacin Lofexidine Lumefantrine Macimorelin Mavacamten Mefloquine Melphalan Methadone Metronidazole Mirtazapine Mobocertinib Moxifloxacin Moxisylyte Nafarelin Netupitant Nilotinib Norfloxacin Nortriptyline Ofloxacin Olanzapine Omaveloxolone Ondansetron Osilodrostat Osimertinib Oxaliplatin Ozanimod Pacritinib Paliperidone Panobinostat Paroxetine Pasireotide Pazopanib Phenobarbital Phenoxybenzamine Phentolamine Pimavanserin Pitolisant Ponesimod Prazosin Primidone Procainamide Prochlorperazine Promethazine Propafenone Protriptyline Quetiapine Quinidine Quinine Quizartinib Ranolazine Relugolix Ribociclib Selpercatinib Sertraline Sevoflurane Silodosin Siponimod Sodium Phosphate Sodium Phosphate, Dibasic Sodium Phosphate, Monobasic Solifenacin Sorafenib Sotalol Sulpiride Sunitinib Tacrolimus Tadalafil Tamsulosin Telavancin Terazosin Tetrabenazine Tolazoline Toremifene Trazodone Triclabendazole Trifluoperazine Trimazosin Trimipramine Triptorelin Urapidil Vandetanib Vardenafil Vemurafenib Vilanterol Vinflunine Voclosporin Zuclopenthixol Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acebutolol Alprenolol Atenolol Betaxolol Bevantolol Bisoprolol Bucindolol Carteolol Carvedilol Celiprolol Dilevalol Diltiazem Esmolol Labetalol Levobunolol Mepindolol Metipranolol Metoprolol Nadolol Nebivolol Oxprenolol Penbutolol Pindolol Propranolol Sildenafil Talinolol Tertatolol Timolol

Tab Store in a well closed container, at room temperature, Below 30°C. Protect from Moisture.