Aliskiren
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Aliskiren is used to treat high blood pressure (hypertension) in people who are at least 6 years old and weigh at least 110 pounds (50 kg).
Aliskiren may also be used for purposes not listed in this medication guide.
Indications
Aliskiren is used to treat high blood pressure (hypertension) in people who are at least 6 years old and weigh at least 110 pounds (50 kg).
Aliskiren may also be used for purposes not listed in this medication guide.
Contraindications
You should not take aliskiren if you are allergic to it.
If you have diabetes, do not take aliskiren together with certain heart or blood pressure medicines, such as:
azilsartan, candesartan , eprosartan , irbesartan , losartan, olmesartan , telmisartan , or valsartan; or benazepril , captopril, enalapril, fosinopril , lisinopril , moexipril, perindopril , quinapril, ramipril, or trandolapril .
Do not give aliskiren to children younger than 2 years old.
You may also need to avoid taking these heart or blood pressure medicines with aliskiren if you have kidney disease.
Tell your doctor if you have or have ever had:
an allergic reaction to any blood pressure medicine; heart problems; diabetes; if you are on a low-salt diet; or kidney disease (or if you are on dialysis).
Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Aliskiren can cause injury or death to the unborn baby if you use the medicine during your second or third trimester.
Do not breastfeed.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Aliskiren may cause serious side effects. Call your doctor at once if you have:
a light-headed feeling, like you might pass out; kidney problems --swelling, urinating less, feeling tired or short of breath; or high blood potassium --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.
Common side effects of aliskiren may include:
diarrhea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Do not use if you are pregnant. Stop using aliskiren and tell your doctor right away if you become pregnant.
High Risk Groups
Do not use if you are pregnant. Stop using aliskiren and tell your doctor right away if you become pregnant.
Adult Dosage
150 mg (150 (150)) 24 hourly PO — (Initial Dose) Maintenance: the dosage may be increased to 300 mg daily if blood pressure is not adequately controlled.
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take aliskiren with or without food, but take it at the same time each day.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking aliskiren. This can lead to very low blood pressure , electrolyte imbalance, or kidney failure .
Your blood pressure will need to be checked often. Your blood may also need to be tested often.
Your treatment may also include diet, exercise, lifestyle changes, and other medications. Follow your doctor's instructions very carefully.
If you have high blood pressure, keep using aliskiren even if you feel well. High blood pressure often has no symptoms.
Keep the medicine in the original container, along with the packet or canister of moisture-absorbing preservative.
Store at room temperature away from moisture and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your current medicines. Many drugs can affect aliskiren, especially:
any other heart or blood pressure medicines; cyclosporine ; itraconazole ; a diuretic or "water pill"; or NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac , indomethacin , meloxicam, and others.
This list is not complete and many other drugs may affect aliskiren. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
2 active brands listed alphabetically.
ALEVIA-V
ActiveATCO LABORATORIES LIMITED
DML: ALEVIA-V
Tabs
RASILEZ
ActiveNOVARTIS PHARMA (PAK) LTD
DML: RASILEZ
Tabs
7 additional records are present but flagged "Unverified / Legacy" and not listed.
