Almitrine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Almitrine is used as a respiratory stimulant in acute respiratory failure such as chronic obstructive pulmonary disease.
Indications
Almitrine is primarily indicated in conditions like Acute exacerbation of hypoxic coadaptation, Chronic respiratory failure in hypoxic load, Respiratory depression after anesthesia, Respiratory depression after drug overdose.
Contraindications
Almitrine is contraindicated in conditions like Hepatic failure, Restrictive lung disease, Primary heart disease.
Side Effects
The severe or irreversible adverse effects of Almitrine, which give rise to further complications include Peripheral neuropathy. The signs and symptoms that are produced after the acute overdosage of Almitrine include Hyperventilation, Hypocapnia. The symptomatic adverse reactions produced by Almitrine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Drowsiness, Irritability, Nausea, Anxiety, Dyspnea, Palpitation, Insomnia, Weight Loss, Burning, Epigastric pain, Increased intracranial pressure, GI disturbance, Heaviness.
Warnings
Almitrine should be used with caution in patient with hepatic disease. The best mean of achieving and maintaining therapeutic levels without toxic accumulation is by intermittent dosing, this avoid the accumulation of drug on continuous dosing.
High Risk Groups
Drug should not be given to Pregnant Mothers, and patients suffering from Liver Malfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
25 to 50 mg (38 (37.5)) 12 hourly PO —
3 mg/kg (3 (3)) As recommended. IV Inf — For 2 hours, in 2-3 div.doses.
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Almitrine was found.
Storage
Tab, Vial
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.