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Medicines/Generics/Aminophylline

Aminophylline

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Aminophylline is a bronchodilator that is used with other medications to treat sudden worsening of the symptoms of asthma, bronchitis , or emphysema . Aminophylline may also be used for purposes not listed in this medication guide.
Indications
Aminophylline is a bronchodilator that is used with other medications to treat sudden worsening of the symptoms of asthma, bronchitis , or emphysema . Aminophylline may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with this medicine if you are allergic to aminophylline or theophylline . If possible before you receive aminophylline, tell your caregivers if you have recently had a fever, or if you have ever had: a stomach ulcer ; seizures ; heart problems; fluid in your lungs; a thyroid disorder; cirrhosis , hepatitis, or other liver problems; kidney disease; or a serious infection called sepsis. Tell your doctor if you smoke or have recently stopped smoking. Smoking can affect your aminophylline dose needs. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. Aminophylline can pass into breast milk and may cause fussiness or other side effects in the nursing baby. Tell your doctor if you are breast-feeding. In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers right away if you have: vomiting or severe nausea; fast or irregular heartbeats; a seizure; high blood sugar --increased thirst, increased urination, dry mouth , fruity breath odor; or low potassium level --leg cramps, constipation , irregular heartbeats, fluttering in your chest, numbness or tingling, muscle weakness or limp feeling. Serious side effects may be more likely in older adults. Common side effects of aminophylline may include: nausea, vomiting, diarrhea; feeling restless or irritable; tremors; increased urination; headache; or sleep problems ( insomnia ). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received aminophylline.
High Risk Groups
In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received aminophylline.
Adult Dosage
0.5 mg/ kg/hr (0.5 (0.5)) As recommended. IV Inf — Maintenance dose. 100 to 300 mg (200 (200)) 8 hourly PO — After food 250 to 500 mg (380 (375)) As recommended. Slow IV — Over 20 min 350 mg (350 (350)) As recommended. IV Inf — Maintain for 12 hours afterloading
Child Dosage
1 to 1.2 mg/kg.hr (1.1 (1.1)) As recommended. IV Infusion — Maintenance for 24 hours or As Required 6 mg/kg (6 (6)) As recommended. IV Infusion — Load for once over 20 minutes
Neonatal Dosage
0.2 mg/kg/hr (0.2 (0.2)) As recommended. Infusion — Maintenance for 24 hrs or as required 5 to 6 mg/kg/hr (5.5 (5.5)) As recommended. Infusion — Load for once over 20 minutes
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can affect aminophylline, especially: cimetidine ; disulfiram ; interferon alfa; lithium; tacrine; ticlopidine ; an antibiotic , or medication to treat tuberculosis ; birth control pills or hormone replacement therapy; heart or blood pressure medication; medication to treat gout or kidney stones ; medicine to treat infections caused by worms such as whipworm, pinworm, roundworm, and hookworm; a sedative such as Valium; or seizure medicine. This list is not complete and many other drugs may affect aminophylline. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Liq Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Suppositories Store in a well closed container. Do not Freeze. Protect from Sunlight and Moisture. Tab, Inj Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.