Amiodarone
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Amiodarone affects the rhythm of your heartbeats . It is used to help keep the heart beating normally in people with life-threatening heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart).
Amiodarone is used to treat ventricular tachycardia or ventricular fibrillation.
Amiodarone is for use only in treating life-threatening heart rhythm disorders.
Indications
Amiodarone affects the rhythm of your heartbeats . It is used to help keep the heart beating normally in people with life-threatening heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart).
Amiodarone is used to treat ventricular tachycardia or ventricular fibrillation.
Amiodarone is for use only in treating life-threatening heart rhythm disorders.
Contraindications
You should not use amiodarone if you have:
a serious heart condition called "AV block" (2nd or 3rd degree), unless you have a pacemaker; a history of slow heartbeats that have caused you to faint; or if your heart cannot pump blood properly.
Amiodarone can cause dangerous side effects on your heart, liver, lungs, or thyroid.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
asthma or another lung disorder; liver disease; a thyroid disorder; vision problems; high or low blood pressure ; an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or if you have a pacemaker or defibrillator implanted in your chest.
Taking amiodarone during pregnancy may harm an unborn baby, or cause thyroid problems or abnormal heartbeats in the baby after it is born. Amiodarone may also affect the child's growth or development (speech, movement, academic skills) later in life. Tell your doctor if you are pregnant or if you become pregnant.
You should not breast-feed while taking this medicine, and for several months after stopping. Amiodarone takes a long time to clear from your body. Talk to your doctor about the best way to feed your baby during this time.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to amiodarone: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat.
Amiodarone takes a long time to completely clear from your body. You may continue to have side effects from this medicine after you stop using it.
Call your doctor at once if you have any of these side effects, even if they occur up to several months after you stop using this medicine:
wheezing, cough, chest pain, cough with bloody mucus, fever; a new or a worsening irregular heartbeat pattern (fast, slow, or pounding heartbeats); a light-headed feeling, like you might pass out; blurred vision, seeing halos around lights (your eyes may be more sensitive to light); liver problems - nausea , vomiting, stomach pain (upper right side), tiredness, dark urine, jaundice (yellowing of the skin or eyes); nerve problems - loss of coordination, muscle weakness, uncontrolled muscle movement, or a prickly feeling in your hands or lower legs; signs of overactive thyroid - weight loss , thinning hair, feeling hot, increased sweating, tremors, feeling nervous or irritable, irregular menstrual periods, swelling in your neck ( goiter ); or signs of underactive thyroid - weight gain, tiredness, depression , trouble concentrating, feeling cold.
Common amiodarone side effects may include:
nausea, vomiting, loss of appetite; or constipation .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Amiodarone can cause dangerous side effects on your heart, liver, lungs, or vision.
You should not take this medicine if you are allergic to amiodarone or iodine , or if you have heart block , a history of slow heartbeats that have caused you to faint, or if your heart cannot pump blood properly.
Call your doctor or get medical help at once if you have: chest pain, fast or pounding heartbeats, trouble breathing, vision problems, upper stomach pain, vomiting , dark urine, jaundice (yellowing of the skin or eyes), or if you cough up blood.
Tell your doctor if you have signs of a thyroid problem, such as weight changes, extreme tiredness, dry skin, thinning hair, feeling too hot or too cold, irregular menstrual periods, or swelling in your neck (goiter).
High Risk Groups
Amiodarone can cause dangerous side effects on your heart, liver, lungs, or vision.
You should not take this medicine if you are allergic to amiodarone or iodine , or if you have heart block , a history of slow heartbeats that have caused you to faint, or if your heart cannot pump blood properly.
Call your doctor or get medical help at once if you have: chest pain, fast or pounding heartbeats, trouble breathing, vision problems, upper stomach pain, vomiting , dark urine, jaundice (yellowing of the skin or eyes), or if you cough up blood.
Tell your doctor if you have signs of a thyroid problem, such as weight changes, extreme tiredness, dry skin, thinning hair, feeling too hot or too cold, irregular menstrual periods, or swelling in your neck (goiter).
Adult Dosage
Scraped Dose — Take amiodarone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
You will receive your first few doses in a hospital setting, where your heart rhythm can be monitored.
If you have been taking another heart rhythm medicine, you may need to gradually stop taking it when you start using amiodarone. Follow your doctor's dosing instructions very carefully.
You may take the tablets with or without food, but take it the same way each time.
It may take up to 3 weeks before your heart rhythm improves. Keep using the medicine as directed even if you feel well.
Amiodarone can have long lasting effects on your body. You may need frequent medical tests while using this medicine and for several months after your last dose.
If you need surgery (including laser eye surgery), tell the surgeon ahead of time that you are using amiodarone.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.
Store at room temperature away from moisture, heat, and light.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Amiodarone takes a long time to completely clear from your body. Drug interactions are possible for up to several months after you stop using amiodarone. Talk to your doctor before taking any medication during this time. Keep track of how long it has been since your last dose of amiodarone.
Many drugs can interact with amiodarone. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
2 active brands listed alphabetically.
AMDRONE
ActiveMACTER INTERNATIONAL (PVT) LTD.
DML: AMDRONE
Inj
E-DRAN
ActiveMEDERA PHARMACEUTICALS (PVT) LTD.
DML: E-DRAN
Tabs
