Amodiaquine
Generic medicine reference
Overview
Amodiaquine is a 4-aminoquinoline antimalarial with an action and uses similar to that of chloroquine. Amodiaquine is not recommended for the prophylaxis of malaria. Amodiaquine is used to treat malaria (intermittent or remittent disease characterized by attacks of chills, fever, and sweating and caused by a parasitic protozoan transferred to the human bloodstream by an anopheles mosquito).
Indications
Amodiaquine is primarily indicated in conditions like Malaria, Nephrogenic and partial pituitary diabetes insipidus.
Contraindications
Amodiaquine is contraindicated in conditions like Malaria prophylaxis.
Side Effects
The severe or irreversible adverse effects of Amodiaquine, which give rise to further complications include Liver damage. Amodiaquine produces potentially life-threatening effects which include Blood dyscrasias, Lupus erythematosus. which are responsible for the discontinuation of Amodiaquine therapy. The symptomatic adverse reactions produced by Amodiaquine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Nausea, Vomiting, Diarrhea, Abdominal cramps, Tinnitus, Irregular heart beat, Tremors, General malaise, Skin pigmentation, Palate pigmentation, Nail-beds pigmentation.
Warnings
It should be used with caution in patients allergic to peanuts, not to be used on broken, infectious skin. It should be used with caution in blockage of the gut (intestinal obstruction).
High Risk Groups
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
35 mg/kg (35 (35)) As recommended. PO — For 3 days.
Child Dosage
5 to 10 mg/kg (7.5 (7.5)) As recommended. Oral — Once a Week
Neonatal Dosage
6.25 mg/kg (6.2 (6.25)) As recommended. oral — Once a week
Drug Interactions
No data regarding the interactions of Amodiaquine was found.
Storage
Tab Store in a well closed container.
Available Brands in Pakistan
10 active brands listed alphabetically.
AMDAQUIN
ActiveZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
DML: AMDAQUIN
SuspTabs
AMONATE
ActiveHIGHNOON LABORATORIES LTD.
DML: AMONATE
Tabs
AMOQUINE
ActivePROGRESSIVE LABORATORIES
DML: AMOQUINE
TabsSusp
BASOQUIN
ActivePFIZER LABORATORIES LTD.
DML: BASOQUIN
TabsSusp
DOSAQUIN
ActiveDOSACO LABORATORIES
DML: DOSAQUIN
Tabs
MASOQUINE
ActiveSAFE PHARMACEUTICAL (PVT) LTD.
DML: MASOQUINE
Syr
PROZOQUIN
ActiveDELUX CHEMICAL INDUSTRIES
DML: PROZOQUIN
SuspTabs
Q-ART
ActiveGENIX PHARMA (PVT) LTD
DML: Q-ART
Tabs
SEMOQUINE
ActiveSEMOS PHARMACEUTICALS (PVT) LTD.
DML: SEMOQUINE
Tabs
UNESOQUINE
ActiveUNEXO LABS (PVT) LTD.
DML: UNESOQUINE
Tabs
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.