Amodiaquine

Amodiaquine is a 4-aminoquinoline antimalarial with an action and uses similar to that of chloroquine. Amodiaquine is not recommended for the prophylaxis of malaria. Amodiaquine is used to treat malaria (intermittent or remittent disease characterized by attacks of chills, fever, and sweating and caused by a parasitic protozoan transferred to the human bloodstream by an anopheles mosquito).

Amodiaquine is primarily indicated in conditions like Malaria, Nephrogenic and partial pituitary diabetes insipidus.

Amodiaquine is contraindicated in conditions like Malaria prophylaxis.

The severe or irreversible adverse effects of Amodiaquine, which give rise to further complications include Liver damage. Amodiaquine produces potentially life-threatening effects which include Blood dyscrasias, Lupus erythematosus. which are responsible for the discontinuation of Amodiaquine therapy. The symptomatic adverse reactions produced by Amodiaquine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Nausea, Vomiting, Diarrhea, Abdominal cramps, Tinnitus, Irregular heart beat, Tremors, General malaise, Skin pigmentation, Palate pigmentation, Nail-beds pigmentation.

It should be used with caution in patients allergic to peanuts, not to be used on broken, infectious skin. It should be used with caution in blockage of the gut (intestinal obstruction).

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

35 mg/kg (35 (35)) As recommended. PO — For 3 days.

5 to 10 mg/kg (7.5 (7.5)) As recommended. Oral — Once a Week

6.25 mg/kg (6.2 (6.25)) As recommended. oral — Once a week

No data regarding the interactions of Amodiaquine was found.

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