Medicines/Generics/Amoxicillin

Amoxicillin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Amoxicillin is a penicillin antibiotic used to treat bacterial infections such as tonsillitis, bronchitis, sinusitis, pneumonia , and infections of the ear, nose, throat, skin, or urinary tract. Amoxicillin clavulanate is a combination of amoxicillin and clavulanate potassium. The amoxicillin fights bacteria, and the clavulanate potassium helps prevent certain bacteria from becoming resistant to amoxicillin. Amoxicillin is also sometimes used together with another antibiotic called clarithromycin ( Biaxin ) to treat stomach ulcers caused by Helicobacter pylori infection . This combination is sometimes used with a stomach acid reducer called lansoprazole ( Prevacid ). Amoxicillin 500mg and 250mg are available as tablets or capsules and as an oral suspension. Many brands and forms of amoxicillin are available, and not all brands are listed on this leaflet.

Indications

Contraindications

You should not use amoxicillin if you are allergic to any penicillin antibiotic, such as ampicillin , dicloxacillin , oxacillin , penicillin, or ticarcillin. To make sure this medicine is safe for you, tell your doctor if you have: kidney disease; mononucleosis (also called "mono"); diarrhea caused by taking antibiotics ; or food or drug allergies (especially to a cephalosporin antibiotic such as Omnicef , Cefzil , Ceftin , Keflex , and others). It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Side Effects

The severe or irreversible adverse effects of Amoxicillin, which give rise to further complications include Pseudomembranous colitis, Thrombocytopenia, Stevens johnson syndrome, Nephrotic syndrome, Eosinophilia, Leucopenia, Neutropenia, Seizures, Agranulocytosis, Interstitial nephritis, Hemolysis, Platelet dysfunction.Amoxicillin produces potentially life-threatening effects which include Anaphylactic shock. which are responsible for the discontinuation of Amoxicillin therapy.The signs and symptoms that are produced after the acute overdosage of Amoxicillin include Crystalluria, Hemorrhagic cystitis.The symptomatic adverse reactions produced by Amoxicillin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Anorexia, Diarrhea, Fever, Abdominal pain, Maculopapular rash, Rashes, Gastritis, Indigestion, Urticarial skin rash, Pseudomembranous colitis, Elevation of liver enzymes, Nausea and vomiting, Cholestatic Jaundice, Hepatitis, Bullous rash, Arrhythmia.

Warnings

Do not use this medication if you are allergic to amoxicillin or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others. Before using amoxicillin, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also, tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy. Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, or spermicide) to prevent pregnancy while taking this medicine. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Amoxicillin will not treat a viral infection such as the common cold or flu. Do not share this medication with another person, even if they have the same symptoms you have. Antibiotic medicines can cause diarrhea. This may happen while you are taking amoxicillin, or within a few months after you stop taking it. This may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking this medicine and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

High Risk Groups

Adult Dosage

0.25 to 0.5 g (0.38 (0.375)) 8 hourly PO,IV,IM — Doses vary according to indication. In typhoid fever and Meningitis , 150 mg/Kg/day in adults and 100-150 mg/kg/day in children should be given. Doses greater than 500 mg is given in divided doses. Scraped Dose — Take amoxicillin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Take amoxicillin at the same time each day. Some forms of amoxicillin may be taken with or without food. Check your medicine label to see if you should take your mediicne with food or not. Shake the oral suspension (liquid) before you measure a dose. Measure liquid medicine with the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). You may mix the liquid with water, milk, baby formula, fruit juice, or ginger ale. Drink all of the mixture right away. Do not save for later use. You must chew the chewable tablet before you swallow it. Swallow the regular tablet whole and do not crush, chew, or break it. If you are taking amoxicillin with clarithromycin and/or lansoprazole to treat stomach ulcer , use all of your medications as directed. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Amoxicillin will not treat a viral infection such as the flu or a common cold . Do not share this medicine with another person, even if they have the same symptoms you have. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Store tablets and capsules at room temperature, away from moisture, heat, and light. Liquid amoxicillin may need to be stored in a refrigerator or at room temperature, depending on the brand. Check your label for storage instructions. If stored in the refrigerator, do not allow it to freeze. Throw away any liquid medicine that is not used within 14 days after it was mixed at the pharmacy.

Child Dosage

20 to 40 mg/kg (30 (30)) 8 hourly Oral — 50 to 100 mg/kg (75 (75)) 6 hourly Intra Muscular — 50 to 100 mg/kg (75 (75)) 6 hourly Intra Venous —

Neonatal Dosage

12.5 to 25 mg/kg (19 (18.75)) 6 hourly Intramuscular — 12.5 to 25 mg/kg (19 (18.75)) 6 hourly Intravenous —

Drug Interactions

Tell your doctor about all your other medicines, especially: any other antibiotics; allopurinol ; probenecid ; or a blood thinner - warfarin , Coumadin , Jantoven; birth control pills. This list is not complete. Other drugs may interact with amoxicillin, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here; to check for interactions, click on the link below.

Storage

Caps Store in a well closed container, Below 40°C. Protect from Moisture. Inj (reconstituted soln) Store at room temperature. Use within 1 hr if kept at room temperature. Oral Susp (reconstituted soln) Store at room temperature or refrigerator. Do not Freeze. Use within 2 weeks if refrigerated and within 1 week if kept at room temperature.

Available Brands in Pakistan

82 active brands listed alphabetically.

Amoxicillin

Available Brands in Pakistan

AF-CILLIN

AMCLAV

AMLANIC

AMOCLAV

AMO-CLAV INJECTION

AMOXICAP

AMOXICILLIN

AMOXICILLIN

AMOXICILLIN

AMOXICILLIN

AMOXICILLIN

AMOXI CLAVE

AMOXIL

AMOXILITE

AMOXILITE PLUS

AMOXIMED

AMOXYCILLIN

AMOXYCILLIN

AUGMENTIN

AUGMENTIN BD

AUGMICLAVE

AXALYN

BACNIL

BACTAMOX PLUS

CALAMOX

CALAMOX DUO

CLA

CLAMENTIN

CLAMENTIN BD

CLAMOXIN

CLAV

CLAVOPIN

CLAVUMOX

CO-AMOXI

CO-FLUX

EFFIMOX

ENMOX

FORTECIN

FORTECIN

GEOMOXIN

GLOXIL

HIZEMOX

JAXCIL

KLAVUTIN

LAVOMOX

LOMENT

MAXIL

MAXIL FORTE

M. CLOX

MENTIN

MENTIN FORTE

MOXEVO

OMXICLV

OSPAMOX

OSPAMOX

OXIMOX

PENBRO

POTENCIN

POTENTIN

RITE

SKYMOX

STAMENTIN

STAVOMOX

SUPRAMOX

SUPRAMOX-T

TERMIBEX

ULTRA MOX

ULTREX

VULAMOX

WERIMOX

WILMOX

WILMOX CHEWABLE

WILMOX FORTE

WISEP

WYMOX

WYMOX

ZAMOCLAV

ZEEMOX