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Medicines/Generics/Amphotericin B

Amphotericin B

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview
Amphotericin B is an antifungal medication that fights infections caused by fungus. Amphotericin B is used to treat serious, life-threatening fungal infections . It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina. Amphotericin B may also be used for purposes not listed in this medication guide.
Indications
Amphotericin B is an antifungal medication that fights infections caused by fungus. Amphotericin B is used to treat serious, life-threatening fungal infections . It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina. Amphotericin B may also be used for purposes not listed in this medication guide.
Contraindications
You should not receive this medicine if you are allergic to any formulation of amphotericin B (Abelcet, AmBisome , Amphocin , Amphotec , or Fungizone ). To make sure amphotericin B is safe for you, tell your doctor if you have: heart disease ; diabetes; kidney disease; an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); if you are receiving blood transfusions; or if you are receiving radiation treatments. Amphotericin B is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether amphotericin B passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; wheezing , difficult breathing; swelling of your face, lips, tongue, or throat. Amphotericin B may cause serious side effects. Call your doctor at once if you have: pale skin, easy bruising; blood in your stools; a light-headed feeling, like you might pass out; seizure (convulsions); jaundice (yellowing of the skin or eyes); build-up of fluid in your lungs --anxiety, sweating, gasping for breath, cough with foamy mucus, chest pain, fast or uneven heart rate; signs of a kidney problem --little or no urination; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; low potassium --confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; or signs of new infection --fever, chills, flu symptoms, mouth and throat ulcers, rapid and shallow breathing. Common side effects of amphotericin B may include: nausea, vomiting, stomach pain, diarrhea; upset stomach , loss of appetite; muscle or joint pain ; headache , ringing in your ears; pain, bruising, or swelling where the medicine was injected; weight loss ; or flushing (warmth, redness, or tingly feeling).
Warnings
amphotericin B is for serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection (yeast infection) of the mouth, esophagus, or vagina. Do not use amphotericin B in larger amounts than recommended. An overdose can cause death.
High Risk Groups
amphotericin B is for serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection (yeast infection) of the mouth, esophagus, or vagina. Do not use amphotericin B in larger amounts than recommended. An overdose can cause death.
Adult Dosage
100 mg (100 (100)) 6 hourly PO — 40 to 80 mg (60 (60)) 6 hourly Buccal —
Child Dosage
0.25 to 1 mg/kg (0.62 (0.625)) As recommended. IV Infusion — Infuse over 6 hours
Neonatal Dosage
0.25 to 1 mg/kg (0.62 (0.625)) As recommended. Infusion — Infuse over 6 hrs.
Drug Interactions
Other drugs may interact with amphotericin B, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Storage
Inj Store in refrigerator. Protect from Sunlight.

Available Brands in Pakistan

2 active brands listed alphabetically.

AMPHOTERICIN

Active

MTI MEDICAL (PVT.) LTD DML: 000801

DML: AMPHOTERICIN

Inj

ANFOTERICINA FADA

Active

MEDIVET (PVT) LTD.

DML: ANFOTERICINA FADA

Inj

1 additional record is present but flagged "Unverified / Legacy" and not listed.