Anagrelide

Anagrelide is used to treat a blood cell disorder called thrombocythemia (also called thrombocytosis ), which occurs when your body produces too many platelet cells. Anagrelide may also be used for purposes not listed in this medication guide.

Anagrelide is used to treat a blood cell disorder called thrombocythemia (also called thrombocytosis ), which occurs when your body produces too many platelet cells. Anagrelide may also be used for purposes not listed in this medication guide.

Tell your doctor if you have ever had: bleeding problems; long QT syndrome (in you or a family member); heart or lung problems; liver disease ; or an electrolyte imbalance (such as low levels of potassium in your blood). It is not known whether anagrelide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. This medicine may affect fertility (your ability to have children). You should not breastfeed while using anagrelide. Anagrelide is not approved for use by anyone younger than 7 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Anagrelide may cause serious side effects. Call your doctor at once if you have: easy bruising or bleeding (nosebleeds, bleeding gums); signs of stomach bleeding --bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; chest pain or pressure; fast or pounding heartbeats, fluttering in your chest, and sudden dizziness (like you might pass out); shortness of breath ; swelling in your lower legs; or blue colored lips or skin. Common side effects of anagrelide may include: fast heartbeats, chest pain, breathing problems; numbness, tingling, burning pain; headache, weakness, dizziness; stomach pain, gas, indigestion, loss of appetite; nausea, vomiting, diarrhea; swelling in your hands or feet; fever, cough, not feeling well; back pain ; or rash, itching. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

0.1 % (0.1 (0.1)) 24 hourly Topical — 0.1% may be used with caution in pediatric patients 1 year of age or older. The safety and efficacy of drug use for longer than 3 weeks in this population have not been established. 0.5 mg (0.5 (0.5)) 6 hourly PO — This is the recomended starting dose. For one week. It is recommended that patients with moderate hepatic impairment start anagrelide therapy at a dose of 0.5 mg/day and be maintained for a minimum of one week with careful monitoring of cardiovascular effects. The dosage increment must not exceed more than 0.5 mg/day in any one-week. To monitor the effect of anagrelide and prevent the occurrence of thrombocytopenia, platelet counts should be performed every two days during the first week of treatment and at least weekly thereafter until the maintenance dosage is reached. 1 mg (1 (1)) 12 hourly PO — This can also be the starting dose. For one week. Dosage should not exceed 10 mg/day or 2.5 mg in a single dose. To monitor the effect of anagrelide and prevent the occurrence of thrombocytopenia, platelet counts should be performed every two days during the first week of treatment and at least weekly thereafter until the maintenance dosage is reached. Scraped Dose — Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG) before and during treatment. You may also need frequent blood tests while taking anagrelide. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. If you need surgery, tell the surgeon ahead of time that you are using anagrelide. Store at room temperature away from moisture, heat, and light.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Anagrelide can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure , depression , mental illness, cancer, malaria, or HIV. Tell your doctor about all your other medicines, especially: an antidepressant; medicine to improve blood flow; a blood thinner (such as warfarin or Coumadin ) or other medicine to treat or prevent blood clots; NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib , diclofenac , indomethacin , meloxicam , and others. This list is not complete. Other drugs may affect anagrelide, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.

Caps Store Between 20°C-25°C. Protect from Sunlight.