Apraclonidine (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Apraclonidine (HCl) is an alpha-2 adrenoceptor agonist, a derivative of clonidine. It reduces the secretions of aqueous humor in the anterior chamber of the eye. Therefore, Apraclonidine (HCl) is used to control intra-ocular pressure (IOP), following laser surgery to the eye. Apraclonidine (HCl) is also used to delay laser treatment or surgery for glaucoma, in patients not adequately controlled by another drug.
Indications
Apraclonidine (HCl) is primarily indicated in conditions like Glaucoma, Post-operative elevation of intraocular pressure.
Contraindications
Apraclonidine (HCl) is contraindicated in conditions like Hypersensitivity, CNS depression.
Side Effects
The severe or irreversible adverse effects of Apraclonidine (HCl), which give rise to further complications include Edema of lids, Foreign body sensation. Apraclonidine (HCl) produces potentially life-threatening effects which include Hypertensive crises, Stroke. which are responsible for the discontinuation of Apraclonidine (HCl) therapy. The signs and symptoms that are produced after the acute overdosage of Apraclonidine (HCl) include Bradycardia, Hypotension, Vomiting, Apnea, Coma, Seizures, Dry mouth, Hypothermia, Irritability, Lethargy, Pallor, Sedation, Somnolence, Diminished reflexes, Conduction disturbances, Transient hypertension, Asthenia, Arrhythmias. The symptomatic adverse reactions produced by Apraclonidine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Blurred vision, Pruritus, Pain, Itching, Malaise, Facial edema, Chest pain, Conjunctivitis, Asthma, Dryness of eye, Discomfort, Hyperemia, Tearing, Foreign body sensation, Keratitis, Belching.
Warnings
It should be used with care in patient with severe cardiovascular disease including hypertension, in patient with a history of vasovagal attacks and in depressed patient.
High Risk Groups
Drug should not be given to Paediatrics, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Apraclonidine (HCl) was found.
Storage
Eye Soln Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.