Auranofin

Auranofin is a form of gold that reduces some of the effects of the inflammatory process in the body. Auranofin is used to treat rheumatoid arthritis (RA) in adults. Auranofin is usually given only to people unable to use other RA medications, or when other treatments did not work or have stopped working. Auranofin will not reverse any cartilage or joint damage that has already occurred in your body. Auranofin may also be used for other purposes not listed in this medication guide.

Auranofin is a form of gold that reduces some of the effects of the inflammatory process in the body. Auranofin is used to treat rheumatoid arthritis (RA) in adults. Auranofin is usually given only to people unable to use other RA medications, or when other treatments did not work or have stopped working. Auranofin will not reverse any cartilage or joint damage that has already occurred in your body. Auranofin may also be used for other purposes not listed in this medication guide.

You should not use auranofin if you are allergic to it, or if you have ever had medical problems caused by using gold therapy, such as: an allergic skin reaction; stomach or intestinal problems; a breathing disorder; a bone marrow disorder; or a severe blood cell disorder. Tell your doctor if you have ever had: a bone marrow disorder or weak immune system; kidney disease; liver disease ; or inflammatory bowel disease . It is not known whether auranofin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using auranofin. Auranofin is not approved for use by anyone younger than 18 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Auranofin may cause serious side effects. Call your doctor at once if you have: pale skin, easy bruising, unusual bleeding (nosebleeds, bleeding gums), purple or red spots under your skin; unusual tiredness, feeling short of breath; severe skin rash or itching; sudden chest pain, wheezing , dry cough, feeling short of breath; severe or ongoing diarrhea, nausea, vomiting, or loss of appetite; black, bloody, or tarry stools; or kidney problems --puffy eyes, swelling in your ankles or feet, blood in your urine, urine that looks foamy. Auranofin may cause more side effects on the stomach than gold injections cause. If you were switched from gold injections to auranofin capsules, tell your doctor if you have concerns about these side effects. You may need to use auranofin for a few months before your symptoms improve. Common side effects of auranofin may include: diarrhea, loose stools; rash, itching; or blisters or ulcers in your mouth, red or swollen gums, trouble swallowing. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You should not use auranofin if you have ever had a severe reaction to gold therapy that affected your skin, lungs, bone marrow, blood cells, or your stomach or intestines. Auranofin contains gold, which may be toxic and can cause symptoms such as rash, itching, mouth sores, or blood in your urine, or severe diarrhea. Call your doctor at once if you have a severe skin rash or itching, mouth sores, severe diarrhea, pale skin, unusual tiredness, easy bruising or bleeding, blood in your urine or stools, or if you cough up blood.

You should not use auranofin if you have ever had a severe reaction to gold therapy that affected your skin, lungs, bone marrow, blood cells, or your stomach or intestines. Auranofin contains gold, which may be toxic and can cause symptoms such as rash, itching, mouth sores, or blood in your urine, or severe diarrhea. Call your doctor at once if you have a severe skin rash or itching, mouth sores, severe diarrhea, pale skin, unusual tiredness, easy bruising or bleeding, blood in your urine or stools, or if you cough up blood.

0.086 mg/kg (0.086 (0.086)) 24 hourly PO — As Required Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take this medicine with a full glass of water. It may take up to 6 months of using this medicine before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 3 or 4 months of treatment. Auranofin can increase your risk of bleeding or infection . You will need frequent medical tests. Your liver and kidney function may also need to be checked. Store auranofin at room temperature away from moisture, heat, and light.

( ) — Not recommended in this age group

Not rexcommended in this age group ( ) —

Tell your doctor about all your other medicines, especially: gold injections; hydroxychloroquine ; penicillamine ; phenytoin ; high doses of steroid medication ( prednisone and others); or drugs that weaken your immune system, such as azathioprine , cyclophosphamide , methotrexate , and others. This list is not complete. Other drugs may affect auranofin, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.

Caps Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.