Azacitidine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Azacitidine oral is used to treat acute myeloid leukemia in people who are in remission but cannot finish other treatments for this condition.
Azacitidine injection is used to treat certain types of bone marrow cancers and blood cell disorders.
Azacitidine may also be used for purposes not listed in this medication guide.
Indications
Azacitidine oral is used to treat acute myeloid leukemia in people who are in remission but cannot finish other treatments for this condition.
Azacitidine injection is used to treat certain types of bone marrow cancers and blood cell disorders.
Azacitidine may also be used for purposes not listed in this medication guide.
Contraindications
You should not use azacitidine if you are allergic to it.
You should not be treated with azacitidine injection if you are allergic to mannitol, or if you have advanced liver cancer .
Tell your doctor if you have ever had:
kidney disease; or liver disease .
Azacitidine can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, you may need to have a negative pregnancy test before starting this treatment. Do not use azacitidine if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine. If you take Onureg , keep using birth control for at least 6 months after your last dose. If you are a man, use effective birth control if your sex partner is able to get pregnant. If you take Onureg, keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Onureg or using Vidaza .
Azacitidine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because this medicine can harm an unborn baby.
You should not breastfeed while using azacitidine. Also do not breastfeed for at least 1 week after your last dose of Onureg .
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Azacitidine may cause serious side effects. Call your doctor at once if you have:
severe ongoing nausea, vomiting , or diarrhea ; redness, swelling, warmth, oozing, or other signs of skin infection ; low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; signs of a lung infection --fever, cough with mucus, chest pain, feeling short of breath; kidney problems --pain in your lower back, blood in your urine, little or no urination, swelling in your feet or ankles; liver problems --upper stomach pain, itching , loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low potassium level --leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or signs of tumor cell breakdown --tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate , tingling in your hands and feet or around your mouth.
Common side effects of azacitidine may include:
fever, chills, bruising, or other signs of low blood cell counts; lung infection ; low potassium ; nausea, vomiting, stomach pain, loss of appetite; constipation, diarrhea; joint pain , pain in your arms or legs; feeling weak or tired; dizziness; or redness where an injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Both men and women using azacitidine should use effective birth control to prevent pregnancy. Azacitidine can harm an unborn baby if the mother or father is using this medicine.
You should not be treated with azacitidine injection if you are allergic to mannitol , or if you have advanced liver cancer .
High Risk Groups
Both men and women using azacitidine should use effective birth control to prevent pregnancy. Azacitidine can harm an unborn baby if the mother or father is using this medicine.
You should not be treated with azacitidine injection if you are allergic to mannitol , or if you have advanced liver cancer .
Adult Dosage
1.25 to 1.666 mg/sq.meter (1.5 (1.458)) As recommended. IV Inf — Upto 2 hours for 5 days a week per 2 weeks
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Other drugs may affect azacitidine, including prescription and over-the-counter medicines, vitamins , and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
solutions,injections,powder Store in a well closed container, Between 15°C-30°C. Protect from Sunlight, Moisture and Heat.
Available Brands in Pakistan
No brands are recorded for this generic.