Azilisartan Medoxomil
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Azilisartan Medoxomil is a prodrug and selective AT1 subtype Angiotensin II Receptor Antagonist.It is hydrolyzed to Azilisartan in GI tract. It blocks the binding of Angiotensin II to the AT1 receptor in vascular smooth muscle and adrenal gland and inhibits effect of Angiotensin.It is given for the treatment of hypertension
Indications
Azilisartan Medoxomil is primarily indicated in conditions like Hypertension.
Contraindications
Azilisartan Medoxomil is contraindicated in conditions like Pregnancy,Lactation.
Side Effects
The symptomatic adverse reactions produced by Azilisartan Medoxomil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Nausea, Diarrhea, Cough, Asthenia, GI disorders, muscle spasm.
Warnings
Discontinue drug in nursing. Avoid fetal and neonatal exposure.Monitor for worsening renal function in patients with renal artery stenosis.Correct volume salt depletion prior to its administration.Drink plenty of fluid while taking Azilisartan. Salt diet with Azilisartan can lead to dizziness and hypotension.Similarly the patients with diarrhea and vomitting are also at risk of developing dizziness and hypotension
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
40 to 80 mg (60 (60)) 24 hourly oral — can be taken with or without food
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Azilisartan Medoxomil was found.
Storage
Store Between 20°C-25°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.