Azlocillin (Na)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Almost 70 years ago, Alexander Fleming reported his discovery of penicillin in 1929. Chain, Flory and their associates succeeded in producing significant quantities of the first penicillin from the cultures of Penicillium notatum in 1940. Ten years later virtually unlimited quantities of penicillin G were available for clinical use. Azlocillin is a broad spectrum penicillin antibiotic. Penicillin is derived directly or indirectly from strains of fungi of the genus Penicillium and other soil inhibiting fungi grown on special culture media. Penicillin are active against most bacteria especially gram positive pathogens (streptococci, staphylococci, pneumococci), some negative strains (gonococci, meningococci), some spirochetes and some fungi. The structure of penicillin consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain.
Indications
Azlocillin (Na) is primarily indicated in conditions like Infection in immunocompromised patients, Meningitis, Urinary tract infection.
Contraindications
Azlocillin (Na) is contraindicated in conditions like Cardiac insufficiency,Hypersensitivity,Hemorrhagic diathesis.
Side Effects
The severe or irreversible adverse effects of Azlocillin (Na), which give rise to further complications include Hypokalemia. The signs and symptoms that are produced after the acute over dosage of Azlocillin (Na) include Renal insufficiency, Neurotoxicity, Epileptic seizures. The symptomatic adverse reactions produced by Azlocillin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Phlebitis.
Warnings
It should be used with caution in patients in whom sodium overload could lead to cardiac insufficiency and in patients with renal dysfunction. Use of Azlocillin should be avoided during first trimester of pregnancy.
High Risk Groups
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
28.571 mg/kg (29 (28.571)) 8 hourly IV — -
Child Dosage
75 to 100 mg/kg (88 (87.5)) 8 hourly Intra Venous — -
Neonatal Dosage
75 to 100 mg/kg (88 (87.5)) 8 hourly Intravenous —
Drug Interactions
No data regarding the interactions of Azlocillin (Na) was found.
Storage
Inj Store in a well closed container, Below 25°C.
Available Brands in Pakistan
No brands are recorded for this generic.