Benserazide (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Benserazide (HCl) is used in Parkinson's disease (mental disorder) with levodopa to reduce its side-effects by preventing peripheral breakdown of LEVODOPA, allowing reduced dosage and decreased side effects.
Indications
Benserazide (HCl) is primarily indicated in conditions like Parkinsonism.
Contraindications
Benserazide (HCl) is contraindicated in conditions like Psychosis,Narrow-angle glaucoma.
Side Effects
The severe or irreversible adverse effects of Benserazide (HCl), which give rise to further complications include Postural hypotension, Psychiatric disturbances, Fluctuating disability, Dyskinesias.Benserazide (HCl) produces potentially life-threatening effects which include Severe postural hypotension. which are responsible for the discontinuation of Benserazide (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Benserazide (HCl) include Hypotension, Nausea, Vomiting, Cardiac arrhythmias, Chorea. The symptomatic adverse reactions produced by Benserazide (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Elevated alkaline phosphatase, Elevated hepatic transaminases.
Warnings
Rapidly affects oxygenation and lung compliance and should be restricted to a highly supervised use in a clinical setting with immediate availability of clinicians experienced with intubation and ventilatory management of the premature infants. If transient episode of the bradycardia and decreased oxygen saturation occur, discontinue the dosing procedure and initiate measures to alleviate the condition, produces rapid improvements in lungs oxygenation and compliance that may require immediate reductions in ventilator settings and FiO2.
High Risk Groups
Drug should not be given to Geriatrics, Neonates, and Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.476 to 0.714 mg/kg (0.59 (0.595)) 8 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Benserazide (HCl) was found.
Storage
Powder Store in a well closed container. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.