Benzathine Penicillin

Benzathine Penicillin has the same antimicrobial activity as benzylpenicillin to which Benzathine Penicillin is hydrolyzed gradually following deep intramuscular injection. Its use should be restricted to micro-organisms that are highly susceptible to benzylpenicillin.

Benzathine Penicillin is primarily indicated in conditions like Acute otitis media, Bacterial infections, Diphtheria carriers, Gonorrhoea, Penicillin sensitive infections, Prophylaxis of rheumatic fever, Streptococcal impetigo, Syphilis.

Benzathine Penicillin is contraindicated in conditions like Seizures.

The severe or irreversible adverse effects of Benzathine Penicillin, which give rise to further complications include Urticaria, Allergic reactions, Serum sickness, Skin reactions.Benzathine Penicillin produces potentially life-threatening effects which include Anaphylactoid reactions, which are responsible for the discontinuation of Benzathine Penicillin therapy.The symptomatic adverse reactions produced by Benzathine Penicillin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Loose stools, Burning discomfort, Local pain, Deep muscle soreness.

Benzathine penicillin should be used with caution in patients with medical history especially of any kidney disease, stomach or intestine diseases or allergies to penicillin or other antibiotics. Use with caution during pregnancy or lactation.

Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

0.6 to 1.2 million units (0.9 (0.9)) As recommended. IM — single dose every 3 weeks dose and duration may vary according to indication

22.9 mg/kg (23 (22.9)) 8 hourly Oral — - 22.9 to 45.8 mg/kg (34 (34.35)) As recommended. Intra Muscular — Every 5-7 Days

28.625 mg/kg (29 (28.625)) 8 hourly oral —

No data regarding the interactions of Benzathine Penicillin was found.

Injections Store in a well closed container, Below 30°C.