Benzbromarone
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Benzbromarone is a uricosuric drug that reduces plasma concentrations of uric acid by blocking renal tubular reabsorption. Benzbromarone may also increase the intestinal elimination of uric acid. It has been used to treat hyperuricaemia including that associated with chronic gout. Benzbromarone is not used to treat acute attacks of gout and may exacerbate and prolong them if given during an attack; treatment should not start therefore until an acute attack has subsided.
Indications
No indications information is recorded for this medicine yet.
Contraindications
Benzbromarone
Side Effects
The severe or irreversible adverse effects of Benzbromarone, which give rise to further complications include Hepatotoxicity, Renal calculi, Renal colic.The symptomatic adverse reactions produced by Benzbromarone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea.
Warnings
Benzbromarone should be avoided in patients with moderate or severe renal impairment, in those with uric acid renal calculi, and in those with urinary uric acid excretion rates of greater than 700 mg per 24 hours. Like other uricosurics, treatment with benzbromarone should not be started during an acute attack of gout. Similarly, an adequate fluid intake should be maintained to reduce the risk of uric acid renal calculi; additionally, alkalinisation of the urine may be considered.
High Risk Groups
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
50 to 300 mg (180 (175)) As recommended. PO —
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Benzbromarone was found.
Storage
Tab, Oint, Gel, Cream, Lotion, Oral Soln Store at room temperature, Below 30°C or in refrigerator. Do not Freeze. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.