Benzhexol (HCl)

Benzhexol (HCl) is anti-spasmodic drug. It relieves the abdominal pain and cramps. Benzhexol (HCl) is used in parkinsonism (mental disorder) of all causes. Like atropine it also causes dry mouth , blurred vision, constipation, confusion and hallucinations. Salicylate of neostigmine is its effective antidote.

Benzhexol (HCl) is primarily indicated in conditions like Extrapyramidal disorders, Parkinsonism, and can also be given in adjunctive therapy as an alternative drug of choice in Advanced ovarian cancer.

Benzhexol (HCl) is contraindicated in conditions like Narrow-angle glaucoma, Hypersensitivity to the drug.

The severe or irreversible adverse effects of Benzhexol (HCl), which give rise to further complications include Tachycardia.The symptomatic adverse reactions produced by Benzhexol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Confusion, Hallucination, Euphoria, Agitation.

People under 18 years of age should not be treated due to a lack of clinical experience. People should allow a period to adjust to the dose when first starting trihexyphenidyl and when the dose has been increased or added to a regimen with other drugs because acute somnolence and accumulated fatigue can make it particularly dangerous to operate an automobile, heavy machinery.

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

1 to 2 mg daily (1.5 (1.5)) 24 hourly PO — Trihexyphenidyl HCl in Idiopathic Parkinsonism:1mg is administered on first day and then increased by 2mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the post-encephalitic group, may require a total daily dose of 12 to 15 mg. 5 to 15 mg daily (10 (10)) 24 hourly PO — Trihexyphenidyl HCl in Drug-Induced Parkinsonism:It may be advisable to commence therapy with a single 1 mg dose. If the extrapyramidal manifestations are not controlled in a few hours, the subsequent doses may be progressively increased until satisfactory control is achieved.

( ) — Not recommended in this age group

( ) — Not recommended in this age group

No data regarding the interactions of Benzhexol (HCl) was found.

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