Betaxolol (HCl)

Betaxolol (HCl) is a cardio selective beta blocker. Betaxolol (HCl) is anti-hypertensive and antianginal agent. It reduces fluid formation in the eye and reduced pressure in the eye produced by glaucoma

Betaxolol (HCl) is primarily indicated in conditions like Angina pectoris, Glaucoma, Hypertension.

Betaxolol (HCl) is contraindicated in conditions like Asthma,Heart failure, Sinus Bradycardia, Second or third degree A-V block, Cardiogenic shock.

Betaxolol (HCl) produces potentially life-threatening effects which include Bronchospasm, Angina. which are responsible for the discontinuation of Betaxolol (HCl) therapy.The symptomatic adverse reactions produced by Betaxolol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Bradycardia, Impotence, Sleep disturbance, Cold hands and feet, GI upset, Raynaud's phenomenon, Palpitation, lethargy.

Betaxolol (beta-blocker) should not be given to patients with bronchospasm, asthma, with history of obstructive airway disease, metabolic acidosis, partial heart block, sinus bradycardia or psoriasis. The dose may need to reduce in patients with renal (kidney) or hepatic (liver) dysfunction. Patients with long term treatment with beta-blockers should have their medication discontinued gradually over a period of 1 to 2 weeks, because it may result in angina, myocardial infraction (MI), ventricular arrhythmia or death. This drug should be used only if clearly needed during pregnancy or lactation.

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

0.25 to 0.5 % (0.38 (0.375)) 24 hourly Ophthalmic — drops. 10 to 20 mg (15 (15)) 24 hourly PO — Gradually Increased 20 to 40 mg (30 (30)) 24 hourly PO —

( ) — Not recommended in this age group

( ) — Not recommended in this age group

Betaxolol (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineSevere hypertension when beta-blockers (e.g Betaoxolol) given with Adrenaline.MajorAmiodarone (HCl)Amiodarone may enhance the hypotensive effect of Betaxolol. Possibly to the point of cardiac arrest.MajorMonitor increased signs and symptoms of bradycardia with Betaxolol (possibly to the point of cardiac arrest) if amiodarone is initiated/dose increased, or decreased effects if amiodarone is discontinued/dose decreased. Ophthalmic beta-blockers are likely of little concern.Clonidine (HCl)Increased risk of withdrawal hypertension when beta-blockers (e.g Betaxolol) given with Clonidine.MajorDigoxinBetaxolol may enhance the bradycardic effect of digoxin.ModerateMonitor bradycardia if these two agents are used concomitantly. Ophthalmic beta-blockers are likely of little concern.Diltiazem (HCl)Increased risk of AV block and bradycardia when beta-blockers (e.g Betaxolol) given with Diltiazem. MajorMetrizamideLimited data suggest that patients receiving beta blockers may have an increased risk of severe hypotensive and/or hypersensitivity reactions to parenteral iodinated contrast media. In addition, the treatment of allergic/anaphylactoid reactions in these patients may be more difficult. The mechanism is unknown. ModeratePatients who have received beta blockers should be closely monitored for adverse reactions to iodinated contrast media. If anaphylaxis occurs, clinicians should be aware that beta blockers may attenuate the response to epinephrine. Thus, larger doses of epinephrine may be necessary to overcome the bronchospasm, although such large doses can also cause excessive alpha adrenergic stimulation resulting in hypertension, reflex bradycardia, heart block, and possible potentiation of bronchospasm. Alternative treatments recommended include vigorous supportive care (e.g., fluids) and the use of parenteral beta agonists for bronchospasm and norepinephrine for hypotension.Ritodrine (HCl)Betaxolol (HCl) may antagonize the effects of ritodrine.Verapamil (HCl)Severe hypotension when and heart failure when beta blockers (e.g Betaxolol) given with Verapamil.Major These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Eye Drops Store Below 40°C. Do not Freeze. Protect from Sunlight.