Biperiden (HCl)
Generic medicine reference
Overview
Biperiden (HCl) is a antimuscarinic and anti-spasmodic agent. Biperiden (HCl) is used as an adjunct in the therapy of parkinsonism (deficiency of dopamine) of all causes.
Indications
Biperiden (HCl) is primarily indicated in conditions like Acute dystonic reactions, Oculogyric crises, Parkinsonism, Pseudo-parkinsonism.
Contraindications
Biperiden (HCl) is contraindicated in conditions like Tardive dyskinesias,Cardiac dysrhythmias.
Side Effects
The severe or irreversible adverse effects of Biperiden (HCl), which give rise to further complications include Toxic confusional state. Biperiden (HCl) produces potentially life-threatening effects which include Cardiac arrhythmias. which are responsible for the discontinuation of Biperiden (HCl) therapy.The signs and symptoms that are produced after the acute over dosage of Biperiden (HCl) include Flushing, Tachycardia, Dilated pupils, Dry mucous membrane, Dry skin.The symptomatic adverse reactions produced by Biperiden (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Dry mouth, GI symptoms.
Warnings
Biperiden should be used with caution in patients with heart, liver, kidney or obstructive gastrointestinal (GI) diseases. Patient should observe caution while driving or performing other tasks requiring alertness because may impair mental or physical abilities. It should be used with caution in hot weather. Reduce dose or discontinue therapy if loss of appetite or weight occur.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.014 to 0.085 mg/kg (0.05 (0.0495)) 8 hourly PO — -
0.035 to 0.285 mg/kg (0.16 (0.16)) 24 hourly IM — -
0.035 to 0.285 mg/kg (0.16 (0.16)) 24 hourly IV — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Biperiden (HCl) was found.
Storage
Inj Store Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Tab Store in a well closed container, Below 40°C. Protect from Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.