Botulinum Toxin Type A

Xeomin, also called botulinum toxin type A, is made from the bacteria that causes botulism . Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity. Xeomin injection is used in adults to treat: muscle spasms and stiffness of the arms (upper limb spasticity); cervical dystonia (severe spasms in the neck muscles), or muscle stiffness in the elbows, wrists, fingers, ankles, or toes; certain eye muscle conditions caused by nerve disorders (including uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction); or to temporarily lessen the appearance of upper facial lines, such as forehead lines, frown lines, and crow's feet (adults over 18 years old). Xeomin is also used in children at least 2 years old to treat; upper limb spasticity that is not caused by cerebral palsy; or chronic drooling (sialorrhea).

Xeomin, also called botulinum toxin type A, is made from the bacteria that causes botulism . Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity. Xeomin injection is used in adults to treat: muscle spasms and stiffness of the arms (upper limb spasticity); cervical dystonia (severe spasms in the neck muscles), or muscle stiffness in the elbows, wrists, fingers, ankles, or toes; certain eye muscle conditions caused by nerve disorders (including uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction); or to temporarily lessen the appearance of upper facial lines, such as forehead lines, frown lines, and crow's feet (adults over 18 years old). Xeomin is also used in children at least 2 years old to treat; upper limb spasticity that is not caused by cerebral palsy; or chronic drooling (sialorrhea).

Botulinum Toxin Type A is contraindicated in conditions like Myasthenia gravis, Pregnancy, Immunocompromised patient, Bleeding diathesis, Breast feeding.

Common Xeomin side effects may include: pain where the medicine was injected; dry mouth, tooth problems; muscle weakness; vision problems; trouble swallowing; dry eyes, drooping eyelids; headache, neck pain, body aches; a seizure; increased blood pressure; diarrhea ; or cold symptoms such as stuffy nose, sneezing, sore throat , cough, and chest congestion.

Xeomin carries a Boxed Warning for the possible distant spread of incobotulinumtoxinA from the site of the injection. The botulinum toxin contained in Xeomin can spread to other body areas beyond where it was injected. This can cause serious life-threatening side effects. Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur several weeks after a Xeomin injection. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection. You should not receive Xeomin injection if you are allergic to botulinum toxin. Get emergency medical help if you have signs of an allergic reaction to Xeomin: hives ; wheezing, difficulty breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat. Do not receive Xeomin injection if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Using Xeomin more often than prescribed will not make it more effective and may result in serious side effects. The effects of a Xeomin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin. Xeomin should be used with caution in patients with marked facial asymmetry, who have undergone surgical facial procedures, with pre-existing eyelid or eyebrow drooping, and some other facial conditions. Talk to your healthcare provider. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Xeomin carries a Boxed Warning for the possible distant spread of incobotulinumtoxinA from the site of the injection. The botulinum toxin contained in Xeomin can spread to other body areas beyond where it was injected. This can cause serious life-threatening side effects. Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur several weeks after a Xeomin injection. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection. You should not receive Xeomin injection if you are allergic to botulinum toxin. Get emergency medical help if you have signs of an allergic reaction to Xeomin: hives ; wheezing, difficulty breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat. Do not receive Xeomin injection if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Using Xeomin more often than prescribed will not make it more effective and may result in serious side effects. The effects of a Xeomin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin. Xeomin should be used with caution in patients with marked facial asymmetry, who have undergone surgical facial procedures, with pre-existing eyelid or eyebrow drooping, and some other facial conditions. Talk to your healthcare provider. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

1.25 to 2.5 units (1.9 (1.875)) As recommended. IM — Dose for Persistent VI nerve palsy of 1 month or longer duration. 2.5 to 5 units (3.8 (3.75)) As recommended. IM — Dose for Horizontal strabismus of 20 to 50 prism diopters. 236 units (240 (236)) As recommended. IM — Dose for Cervical Dystonia 4 units (4 (4)) As recommended. IM — Dose for Glabellar Lines: dose should be injected into each of five sites, two in each corrugator muscle and one in the procerus muscle for a total of 20 units. 50 units (50 (50)) As recommended. ID — Dose for Hyperhidrosis: sual dose should be injected intradermally in 0.1 to 0.2 mL aliquots to each axilla distributed evenly in multiple sites (10 to 15) 1 to 2 cm apart.

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Other medicines can increase some of the side effects of Xeomin. Tell your doctor about all your other medicines, especially: an antibiotic such as amikacin, gentamicin, kanamycin, neomycin, paromomycin, streptomycin, tobramycin; muscle relaxers; medicine to treat depression, anxiety, mood disorders, or mental illness; cold or allergy medicine (Benadryl and others); medicine to treat Parkinson's disease; medicine to treat stomach problems, motion sickness, or irritable bowel syndrome; medicine to treat an overactive bladder; or bronchodilator asthma medication. This list is not complete. Other drugs may interact with incobotulinumtoxinA, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.

IM Inj Store in refrigerator.