Medicines/Generics/Caffeine

Caffeine

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Caffeine is a central nervous system stimulant. It works by stimulating the brain. Caffeine is found naturally in foods and beverages such as coffee, tea, colas, energy and chocolate. Botanical sources of caffeine include kola nuts, guarana , and yerba mate. Caffeine is also available in prescription and non-prescription medications. Caffeine is used to restore mental alertness or wakefulness during fatigue or drowsiness. Caffeine is also found in some headache and migraine medications, in certain dietary supplements used for weight loss, and in many popular energy drinks. Caffeine citrate ( Cafcit ) is available by prescription only. It is used for short-term treatment of neonatal apnea (breathing problems). Caffeine may also be used for other conditions as determined by your health care provider.

Indications

Contraindications

Caffeine is contraindicated in conditions like Cardiac arrhythmia, Peptic ulcer, Hypersensitivity.

Side Effects

difficulty sleeping (insomnia) nervousness or anxiety irritability nausea headache Seek medical attention right away if any of these severe side effects occur: serious allergic reactions (difficult breathing, chest tightness, swelling of the mouth, face, lips, or tongue, rash, hives, or itching) diarrhea vomiting rapid heart rate or palpitations increased blood pressure chest pain This is not a complete list of all side effects that may occur. Call your health care provider for medical advice about side effects.

Warnings

Caffeine should be used with caution in diabetic patients because it may produced hyperglycemia, in anxiety disorder or panic disorder because it can aggravate these conditions, in hepatic disease or hepatic impairment and during pregnancy and breast feeding.

High Risk Groups

Drug should not be given to patients suffering from Liver Malfunction, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

100 to 200 mg (150 (150)) As recommended. PO,IV —

Child Dosage

10 mg/kg (10 (10)) As recommended. Intravenous — Load for Once 10 mg/kg (10 (10)) As recommended. Oral — Load for Once 2.5 (2.5 (2.5)) As recommended. Intravenous — Maintenance 2.5 mg/kg (2.5 (2.5)) As recommended. Oral — Maintenance, As Required

Neonatal Dosage

Drug Interactions

Caffeine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholCimetidine (HCl)CinoxacinCiprofloxacinCoadministration inhibit the metabolism of caffeine thus increasing its plasma concentration and pharmacological effect.Ciprofloxacin increases caffeine AUC by 50% to over 100% and reduces its clearance upto 50%.ModerateCaffeine intake should be avoided during treatment that may increase the risk of adverse effects like tremor,insomnia,tachycardia and blood pressure.DiazepamDipyridamoleDisulfiramDue to inhibition of caffeine metabolism in liver microsomes its concentration may be increases in cardiovascular and CNS .MinorCaffeine intake should be limited while taking disulfiram.EnoxacinFenoterol Use of Fenoterol with caffeine may increase risk of hypokalemia. Frusemide or FurosemideIron SaltsLevonorgestrelMexiletineNimodipineNorfloxacinPentobarbitone (Na)Phenytoin (Na)Pipemidic AcidRiluzoleCaffeine could decrease the rate of riluzole elimination. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Storage

Tab Store at room temperature. Protect from Sunlight, Moisture and Heat.

Available Brands in Pakistan

59 active brands listed alphabetically.

Caffeine

Available Brands in Pakistan

AMADOL EXTRA

AMIDOL

AMOLE PLUS

AMSIPOL

AMTALIDIN

ARIDOL

CAFFEINE CITRATE

CAFIPAR

CALPOL PLUS

CAYDOL EXTRA

C.C DON EXTRA

CHILPOL EXTRA

CURIDOL EXTRA

DELMOL EXTRA

DETAMOL EXTRA

DIAGESIC-P

ESTADOL EXTRA

EXCEDRIN-XTRA

FEBRICOD C

FEBROL XTRA

FEDRAMOL PLUS

FEMIDOL PLUS

FENMOL EXTRA

FENMOL PLUS

FEVAMOL EXTRA

HIZEDOL

IRZAPOLE PLUS

JETAMOL EXTRA

MEDIGESIC C

MEDIGESIC FORTE

MIGRIL

NOPAIN AF

NUBEROL PLUS

OPTALIDON

PAMOL X

PANADOL EXTRA

PANAFIN EXTRA

PARA-CAFFIN

PARACETAMOL COMPOUND

PARAGRAY EXTRA

PARAHEIM PLUS

PARA+PLUS

PARATOL EXTRA

PAROL PLUS

PEDROL EXTRA

PEYONA

PREGESIC

PYRECAF PLUS

PYROL EXTRA

RASCODOL PLUS

RGESIC EXTRA

SYNADOC

TEMPOL-C

TERINOL

TRIGIN

TYLADOL EXTRA

TYLOL EXTRA

VIGROL FORTE

WYLADOL EXTRA