Question 1

What is Calcipotriol used for?

Accepted Answer

Enstilar foam is a once-daily, topical, fixed-dose combination foam containing calcipotriene 0.005% (a vitamin D analog) and betamethasone dipropionate 0.064% (a corticosteroid) that may be used to treat plaque psoriasis in adults and children 12 years of age or older.

Enstilar foam is a stable supersaturated solution of calcipotriol/betamethasone dipropionate that has improved clinical efficacy and increased skin penetration compared with standard calcipotriol/betamethasone dipropionate ointments.

Enstilar was approved on October 16, 2015.

Question 2

What is the adult dose of Calcipotriol?

Accepted Answer

0.005 % (0.005 (0.005)) 12 hourly Topical — -

Question 3

What is the paediatric dose of Calcipotriol?

Accepted Answer

( )     — Not recommended in this age group

Question 4

What are the side effects of Calcipotriol?

Accepted Answer

The most common side effects reported with Enstilar include irritation or itch at the application site, folliculitis (inflammation of the hair follicles), skin hypopigmentation (areas of skin lose their color), high calcium levels, itch, and a flare-up of psoriasis.

Postmarketing studies with topical corticosteroids have reported skin thinning, stretch marks, broken superficial blood vessels (telangiectasia), itching, dryness, dermatitis around the mouth, secondary infection, and miliaria (heat rash).

Side effects affecting the eye including cataracts, glaucoma, and increased intraocular pressure, have been reported during the use of topical corticosteroids, including topical betamethasone products.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Question 5

Who should not take Calcipotriol?

Accepted Answer

You should not use Enstilar foam if you are allergic to calcipotriene, betamethasone dipropionate, or any other components of the foam.

Tell your doctor if you have ever had:

too much calcium in your blood or urine an adrenal gland disorder cataracts or glaucoma liver disease severe forms of psoriasis (with pus, skin peeling, severe redness) have thinning skin at the treatment site a skin infection or if you are receiving UV light treatments (phototherapy).

Question 6

What does Calcipotriol interact with?

Accepted Answer

Tell your doctor about all your other medicines, especially:

any other steroid medicine (such as dexamethasone, fludrocortisone, hydrocortisone, prednisone, triamcinolone, and others); or any other medicine to treat psoriasis.

This list is not complete. Other drugs may affect Enstilar foam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed.

Calcipotriol

Available Brands in Pakistan

CALCIDERM

CALCIPOT

CALPSOR

CARTRIAL

CIPOTROL

DAIVONEX

DERIVAX

DERMA-D

DERVIT

EVONEX

POTRIOL

SORIODAN