Carboplatin

Carboplatin belongs to a class of medications known as platinum-containing compounds. It works by stopping or slowing the growth of cancer cells. Carboplatin is used in adults in combination with other cancer treatments to treat ovarian cancer . Carboplatin is also used in adults who have advanced ovarian carcinoma, where ovarian cancer has returned following prior chemotherapy, and are receiving palliative care (treatment to relieve suffering and improve quality of life during a serious illness).

Carboplatin belongs to a class of medications known as platinum-containing compounds. It works by stopping or slowing the growth of cancer cells. Carboplatin is used in adults in combination with other cancer treatments to treat ovarian cancer . Carboplatin is also used in adults who have advanced ovarian carcinoma, where ovarian cancer has returned following prior chemotherapy, and are receiving palliative care (treatment to relieve suffering and improve quality of life during a serious illness).

You should not be treated with carboplatin if you are allergic to it, or if you have: severe bleeding; severe bone marrow suppression; or if you have had a severe allergic reaction to similar cancer drugs such as oxaliplatin or cisplatin . To make sure this medicine is safe for you, tell your doctor if you have ever had: if you have recently been exposed to varicella (chickenpox), or have varicella (chickenpox); shingles ( herpes zoster ); hearing problems; weak immune system (caused by disease or by using certain medicines); if you have received carboplatin in the past; liver disease; or kidney disease. Carboplatin may harm an unborn baby. Use birth control and tell your doctor if you become pregnant. Do not breastfeed while receiving this medicine.

Get emergency medical help if you have signs of an allergic reaction to carboplatin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Some side effects may occur during the injection. Tell your medical caregivers if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache , chest tightness, back pain , trouble breathing, or swelling in your face. Carboplatin may cause serious side effects. Call your doctor at once if you have: severe or ongoing nausea and vomiting; numbness or tingly feeling in your hands or feet; vision problems; hearing problems, ringing in your ears; pain, burning, irritation, or skin changes where the injection was given; signs of infection - fever, chills, sore throat , body aches, unusual tiredness, loss of appetite, bruising or bleeding; liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or signs of an electrolyte imbalance - increased thirst or urination, constipation , muscle weakness, leg cramps, numbness or tingling, feeling jittery, fluttering in your chest. Common carboplatin side effects may include: low blood cell counts; loss of appetite; nausea , vomiting , diarrhea ; numbness, burning pain, or tingly feeling; temporary hair loss ; or pain in your hands or feet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may have a severe allergic reaction shortly after receiving a carboplatin injection. Your medical caregivers will quickly treat you if this occurs. You may be given medicine prior to the injection to help prevent an allergic reaction. You may get infections or bleed more easily. Call your doctor if you have unusual bleeding or signs of infection ( fever , cough , skin sores, painful urination).

You may have a severe allergic reaction shortly after receiving a carboplatin injection. Your medical caregivers will quickly treat you if this occurs. You may be given medicine prior to the injection to help prevent an allergic reaction. You may get infections or bleed more easily. Call your doctor if you have unusual bleeding or signs of infection ( fever , cough , skin sores, painful urination).

400 mg/sq.meter (730 (733)) As recommended. IV Inf — Once over 15-60 Minutes

No child dosage information is recorded for this medicine yet.

No neonatal dosage information is recorded for this medicine yet.

Carboplatin can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis , organ transplant rejection, high blood pressure , or pain or arthritis (including Advil , Motrin , and Aleve ). Tell your doctor about all your current medicines. This list is not complete and many Other drugs may interact with carboplatin. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.

Inj (reconstituted soln) Store at room temperature. Use within 8 hrs if kept at room temperature. IV inf Store at room temperature.