Carmustine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Carmustine is used in adults alone or in combination with other cancer treatments to treat brain tumors, Hodgkin's disease , multiple myeloma , and non-Hodgkin's lymphoma .
Carmustine may also be used for purposes not listed in this medication guide.
Indications
Carmustine is used in adults alone or in combination with other cancer treatments to treat brain tumors, Hodgkin's disease , multiple myeloma , and non-Hodgkin's lymphoma .
Carmustine may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with carmustine if you are allergic to it.
Tell your doctor if you have or have ever had:
lung disease or breathing problems; bone marrow suppression; or kidney disease.
Receiving carmustine injection may increase your risk of developing other cancers. Ask your doctor about this risk.
Carmustine can harm an unborn baby if the mother or the father is using carmustine.
If you are a woman, you will need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 6 months after your last dose. If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs.
It may be harder for you to get a woman pregnant while you are using this medicine. You should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Do not breastfeed while receiving carmustine, or for at least 7 days after carmustine implant placement.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your medical caregivers if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache , chest tightness, back pain , trouble breathing, or swelling in your face.
Carmustine can cause serious or fatal lung problems, even months or years after you've used carmustine.
You may also bleed or get infections more easily, including serious or fatal infections. Call your doctor right away if you have:
shortness of breath on exertion; chest discomfort, dry cough or hack; mouth sores, red or swollen gums; feeling weak or tired, loss of appetite, rapid weight loss ; unusual bleeding, pale skin, easy bruising; fever, chills, sore throat , night sweats; or confusion, vision problems.
Also call your doctor at once if you have:
a seizure; little or no urination; abnormal liver function tests; pain, bruising, swelling, or irritation where the medicine was injected; slow healing of your incision after carmustine implant placement; increased pressure inside the skull --severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or signs of meningitis --fever, headache, neck stiffness, increased sensitivity to light, nausea, vomiting , confusion, drowsiness .
Common side effects of carmustine may include:
feeling weak or tired; abnormal wound healing; kidney problems; constipation , fever; urinary tract infections; depression , swelling in your head; low blood cell counts; nausea, vomiting; or breathing problems.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You may get infections or bleed more easily, including serious or fatal infections. Call your doctor if you have shortness of breath on exertion, chest discomfort, dry cough or hack, feeling weak or tired, rapid weight loss, unusual bleeding, fever, painful urination, night sweats, neck stiffness, confusion, or vision problems.
Carmustine can cause serious or fatal lung problems, even months or years after you've used this medicine.
High Risk Groups
You may get infections or bleed more easily, including serious or fatal infections. Call your doctor if you have shortness of breath on exertion, chest discomfort, dry cough or hack, feeling weak or tired, rapid weight loss, unusual bleeding, fever, painful urination, night sweats, neck stiffness, confusion, or vision problems.
Carmustine can cause serious or fatal lung problems, even months or years after you've used this medicine.
Adult Dosage
80 mg/sq.meter (150 (147)) 24 hourly IV Inf — Over 2 Hours for 3 Days
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Tell your doctor about all your other medicines, especially:
seizure medicine such as phenobarbital ; or cimetidine .
This list is not complete. Other drugs may affect carmustine, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.
Storage
Inj (reconstituted soln) Store at room temperature or refrigerator. Protect from Sunlight. Use within 8 hrs if kept at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.