Cefpirome
Generic medicine reference
Overview
Cefpirome is a fourth generation cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporanic acid and are closely related to penicillin in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cefpirome is effective in a large variety of bacterial infections, such as respiratory tract, ear, skin, septicemia, infections in immunocompromised patients and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cefpirome is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Indications
Cefpirome is primarily indicated in conditions like Bacteremia, Lower respiratory tract infections, Pneumonia, Promyelocytic leukemia, Severe infections including bacteraemia and septicaemia and infections in neutropenic patients, Skin infections, Soft tissue infections, Urinary tract infection.
Contraindications
Cefpirome is contraindicated in conditions like Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Cefpirome, which give rise to further complications include Thrombocytopenia, Hemolytic anemia, Hemolytic anemia, Granulocytopenia, Eosinophilia, Agranulocytosis, Eelvated hepatic enzymes, Superinfection.Cefpirome produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Cefpirome therapy. The symptomatic adverse reactions produced by Cefpirome are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Rashes, Urticaria, Pseudomembranous colitis, Increase in liver enzymes.
Warnings
Cefpirome should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 to 2 g (1.5 (1.5)) 12 hourly IV —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Cefpirome was found.
Storage
Powder Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
11 active brands listed alphabetically.
CEFROM
ActiveSANOFI AVENTIS (PAKISTAN) LTD.
DML: CEFROM
Inj
EFPIRO
ActiveNEUTRO PHARMA (PVT) LTD.
DML: EFPIRO
Inj
EFROME
ActiveAKSON PHARMACEUTICALS (PVT) LTD.
DML: EFROME
Inj
IPROME
ActiveSIZA INTERNATIONAL (PVT) LTD.
DML: IPROME
Inj
IVCEF
ActiveBOSCH PHARMACEUTICALS (PVT) LTD.
DML: IVCEF
Inj
MORICEF
ActiveSHROOQ PHARMACEUTICALS
DML: MORICEF
Inj
ORPAC
ActiveSHAWAN PHARMACEUTICALS
DML: ORPAC
Inj
PIR
ActiveELKO ORGANIZATION (PVT) LTD.
DML: PIR
Inj
PIROMECEF
ActiveLOWITT PHARMACEUTICALS (PVT) LTD
DML: PIROMECEF
Inj
PIROXIMAK
ActiveAKSON PHARMACEUTICALS (PVT) LTD.
DML: PIROXIMAK
Tabs
ROMICEF
ActiveBARRETT HODGSON PAKISTAN (PVT) LTD.
DML: ROMICEF
Inj
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.