This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Cefpirome is a fourth generation cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporanic acid and are closely related to penicillin in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cefpirome is effective in a large variety of bacterial infections, such as respiratory tract, ear, skin, septicemia, infections in immunocompromised patients and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cefpirome is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Indications
Cefpirome is primarily indicated in conditions like Bacteremia, Lower respiratory tract infections, Pneumonia, Promyelocytic leukemia, Severe infections including bacteraemia and septicaemia and infections in neutropenic patients, Skin infections, Soft tissue infections, Urinary tract infection.
Contraindications
Cefpirome is contraindicated in conditions like Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Cefpirome, which give rise to further complications include Thrombocytopenia, Hemolytic anemia, Hemolytic anemia, Granulocytopenia, Eosinophilia, Agranulocytosis, Eelvated hepatic enzymes, Superinfection.Cefpirome produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Cefpirome therapy. The symptomatic adverse reactions produced by Cefpirome are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Rashes, Urticaria, Pseudomembranous colitis, Increase in liver enzymes.
Warnings
Cefpirome should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 to 2 g (1.5 (1.5)) 12 hourly IV —
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
No data regarding the interactions of Cefpirome was found.
