Ceftizoxime (Na)

Ceftizoxime is a third generation, semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporanic acid and are closely related to penicillin in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Ceftizoxime is a broad spectrum, ß lactamase resistant antibiotic effective against a wide range of aerobic and anaerobic gram positive and gram negative bacteria. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Ceftizoxime (Na) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.

Ceftizoxime (Na) is primarily indicated in conditions like Bacteremia, Genitourinary tract infections, Intra-abdominal infections, Lower respiratory tract infections, Septicemia, Skin infections, Soft tissue infections, and can also be given in adjunctive therapy as an alternative drug of choice in Bacterial infections, Bone and joint infection, Gonorrhea, Gynecological infections, Meningitis, Surgical prophylaxis.

Ceftizoxime (Na) is contraindicated in conditions like Hypersensitivity to any component of product.

The severe or irreversible adverse effects of Ceftizoxime (Na), which give rise to further complications include Thrombocytopenia, Hypersensitivity reactions, Eosinophilia, Leucopenia, Neutropenia, Thrombocytosis. Ceftizoxime (Na) produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis, Diarrhea. which are responsible for the discontinuation of Ceftizoxime (Na) therapy. The symptomatic adverse reactions produced by Ceftizoxime (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Fever, Rashes, Pruritus, Local reactions, Nausea and vomiting, Elevated alkaline phosphatase, Elevated SGPT & SGOT.

Ceftizoxime should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.

Drug should not be given to patients suffering from Kidney dysfunction. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

1000 to 2000 mg (1500 (1500)) 12 hourly IM/IV —

50 mg/kg (50 (50)) 8 hourly Intra Muscular — - 50 mg/kg (50 (50)) 8 hourly Intra Venous — -

50 mg/kg (50 (50)) 8 hourly Intramuscular — 50 mg/kg (50 (50)) 8 hourly Intravenous —

No data regarding the interactions of Ceftizoxime (Na) was found.

Inj Store Below 40°C. Protect from Sunlight.