This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.
Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis , ankylosing spondylitis , and menstrual pain .
Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.
Elyxyb is used to treat migraine headaches with or without aura in adults. Elyxyb will only treat migraine headaches, but it will not prevent a headache that has already begun.
Indications
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.
Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis , ankylosing spondylitis , and menstrual pain .
Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.
Elyxyb is used to treat migraine headaches with or without aura in adults. Elyxyb will only treat migraine headaches, but it will not prevent a headache that has already begun.
Contraindications
You should not use celecoxib if you are allergic to it, or if you have:
an allergy to sulfa drugs; or a history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.
To make sure celecoxib is safe for you, tell your doctor if you have ever had:
a stomach ulcer , bleeding in your stomach or intestines; heart disease, high blood pressure ; asthma; bleeding problems; liver or kidney disease; or if you smoke or drink alcohol.
If you are pregnant, you should not take celecoxib unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
This medicine may affect fertility (ability to have children) in women. Ask your doctor about this risk.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Do not give this medicine to a child without medical advice.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to celecoxib ( hives , difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.
Stop using celecoxib and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Stop using this medicine and call your doctor at once if you have:
the first sign of any skin rash, no matter how mild; heart problems - swelling, rapid weight gain, feeling short of breath; signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems - nausea , stomach pain (upper right side), itching, tiredness, dark urine, jaundice (yellowing of the skin or eyes); kidney problems - little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Common celecoxib side effects may include:
stomach pain, heartburn , gas, diarrhea , constipation , nausea, vomiting ; swelling in your hands or feet; dizziness ; or cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Celecoxib can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Celecoxib may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.
High Risk Groups
Celecoxib can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Celecoxib may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.
Adult Dosage
Scraped Dose — Take celecoxib exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.
You may take celecoxib with or without food.
Measure liquid medicine with the supplied measuring device (not a kitchen spoon).
If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture with water. You may save this applesauce mixture for later use in a refrigerator for up to 6 hours.
Store at room temperature away from moisture and heat.
Child Dosage
100 mg (100 (100)) 12 hourly for childeren behaving over 25kg —
5 mg (5 (5)) 12 hourly for childeren behaving 10 to 25kg —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Ask your doctor before using celecoxib if you take an antidepressant, steroid medicine, or medicine to treat or prevent blood clots. Taking certain medicines with an NSAID may increase your risk of a stomach ulcer or bleeding.
Many drugs can interact with celecoxib. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Caps Store in a well closed container, Between 20°C-25°C. Protect from Moisture and Heat.
