Chenodeoxycholic Acid
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Chenodeoxycholic Acid is a natural occuring bile acid. It prevents formation and helps in dissolution of gall stones.
Indications
Chenodeoxycholic Acid is primarily indicated in conditions like Cerebrotendinous xanthomatosis, Gall stones.
Contraindications
Chenodeoxycholic Acid is contraindicated in conditions like Calcified gallstones, Chronic liver disease,Non-functioning gallbladders.
Side Effects
The severe or irreversible adverse effects of Chenodeoxycholic Acid, which give rise to further complications include Hepatotoxicity, Hepatotoxicity, hypertransaminasemia, Hypertransaminasemia.Chenodeoxycholic Acid produces potentially life-threatening effects which include Colonic cancer. which are responsible for the discontinuation of Chenodeoxycholic Acid therapy.The symptomatic adverse reactions produced by Chenodeoxycholic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea.
Warnings
Chenodeoxycholic acid should not be administered to patients with chronic liver disease, peptic ulcer or inflammatory bowl disease. Its use should be avoided in pregnancy.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
13 to 15 mg/kg (14 (14)) 24 hourly PO — -
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Chenodeoxycholic Acid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAluminium Hydroxide and OxideCharcoal (Activated)CholestyramineColestipol (HCl)Magnesium Oxides and HydroxidesUrsodeoxycholic Acid These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tabs Store . Protect from Sunlight, Moisture and Heat.
Available Brands in Pakistan
No brands are recorded for this generic.