Chloroform
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Methylene chloride, also called dichloromethane, is a volatile, colorless liquid with a chloroform-like odor. Methylene chloride is used in various industrial processes in many different industries: paint stripping, pharmaceutical manufacturing, paint remover manufacturing, metal cleaning and degreasing, adhesives manufacturing and use, polyurethane foam production, film base manufacturing, polycarbonate resin production, and solvent distribution and formulation. OSHA considers methylene chloride to be a potential occupational carcinogen. Short-term exposures to high concentrations may cause mental confusion, lightheadedness, nausea, vomiting, and headache. Continued exposure may also cause eye and respiratory tract irritation. Exposure to methylene chloride may make symptoms of angina more severe. Skin exposure to liquid methylene chloride may cause irritation or chemical burns. [ 1 ]
Indications
Methylene chloride, also called dichloromethane, is a volatile, colorless liquid with a chloroform-like odor. Methylene chloride is used in various industrial processes in many different industries: paint stripping, pharmaceutical manufacturing, paint remover manufacturing, metal cleaning and degreasing, adhesives manufacturing and use, polyurethane foam production, film base manufacturing, polycarbonate resin production, and solvent distribution and formulation. OSHA considers methylene chloride to be a potential occupational carcinogen. Short-term exposures to high concentrations may cause mental confusion, lightheadedness, nausea, vomiting, and headache. Continued exposure may also cause eye and respiratory tract irritation. Exposure to methylene chloride may make symptoms of angina more severe. Skin exposure to liquid methylene chloride may cause irritation or chemical burns. [ 1 ]
Contraindications
Chloroform is contraindicated in conditions like Diabetes mellitus, Sepsis.
Side Effects
The severe or irreversible adverse effects of Chloroform, which give rise to further complications include Nephrotoxicity, Cardiac arrhythmias, Hepatotoxicity, Hypotension, Decreased cardiac output. Chloroform produces potentially life-threatening effects which include Respiratory depression, Cardiac Arrest. which are responsible for the discontinuation of Chloroform therapy. The symptomatic adverse reactions produced by Chloroform are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritation, Burns of skin & mucous membrane, Blistering.
Warnings
Patients should observe caution while driving or performing other tasks requiring alertness, because it may cause drowsiness. Patients with chronic disease such as diabetes or hypertension may require adjustment to their therapy before anesthesia. Anesthetics (chloroform) should be given with caution in patients with cardiac, respiratory, kidney or liver impairment. Not to vaporize in presence to flame because of production of harmful gases.
High Risk Groups
Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
No adult dosage information is recorded for this medicine yet.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Chloroform was found.
Storage
Liq, Spirit Store in a well closed container. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.