Medicines/Generics/Chymotrypsin

Chymotrypsin

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Chymotrypsin is a proteolytic enzyme. Chymotrypsin is secreted by the pancreas as the inactive pro-enzyme chymotripsinogen. Chymotrypsin is a serine endopeptidase that preferentially cleaves peptide bonds on the carboxyl side of amino acids with bulky hydrophobic residues, particularly tyrosine, tryptophan, phenylalanine and leucine. Chymotrypsin is effective in reducing soft tissue inflammation especially associated with trauma.

Indications

Chymotrypsin is primarily indicated in conditions like Edema, Inflammation, Trauma.

Contraindications

Chymotrypsin is contraindicated in conditions like Peptic ulcer, Renal diseases, Hepatic disease, Tuberculosis, Hypersensitivity to any component of product.

Side Effects

The symptomatic adverse reactions produced by Chymotrypsin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypersensitivity reactions, Corneal edema, Uveitis.

Warnings

The use of chymotrypsin is inadvisable in ocular surgery for patients under 20 years of age or patients with congenital character or high vitreous pressure.

High Risk Groups

Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

100000 IU (100000 (100000)) 6 hourly PO — Half hour before meal

Child Dosage

No child dosage information is recorded for this medicine yet.

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

No data regarding the interactions of Chymotrypsin was found.

Storage

Powder Store in a well closed container. Refrigeration is recommended. Protect from Sunlight and Moisture.