Chymotrypsin
Generic medicine reference
Overview
Chymotrypsin is a proteolytic enzyme. Chymotrypsin is secreted by the pancreas as the inactive pro-enzyme chymotripsinogen. Chymotrypsin is a serine endopeptidase that preferentially cleaves peptide bonds on the carboxyl side of amino acids with bulky hydrophobic residues, particularly tyrosine, tryptophan, phenylalanine and leucine. Chymotrypsin is effective in reducing soft tissue inflammation especially associated with trauma.
Indications
Chymotrypsin is primarily indicated in conditions like Edema, Inflammation, Trauma.
Contraindications
Chymotrypsin is contraindicated in conditions like Peptic ulcer, Renal diseases, Hepatic disease, Tuberculosis, Hypersensitivity to any component of product.
Side Effects
The symptomatic adverse reactions produced by Chymotrypsin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypersensitivity reactions, Corneal edema, Uveitis.
Warnings
The use of chymotrypsin is inadvisable in ocular surgery for patients under 20 years of age or patients with congenital character or high vitreous pressure.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
100000 IU (100000 (100000)) 6 hourly PO — Half hour before meal
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Chymotrypsin was found.
Storage
Powder Store in a well closed container. Refrigeration is recommended. Protect from Sunlight and Moisture.
Available Brands in Pakistan
2 active brands listed alphabetically.
CHYMORAL
ActiveAGP (PRIVATE) LTD.
DML: CHYMORAL
Tabs
CHYMORAL FORTE
ActiveAGP (PRIVATE) LTD.
DML: CHYMORAL FORTE
Tabs
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.