Cidofovir
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Cidofovir is an antiviral medicine that is used to treat an eye infection called cytomegalovirus retinitis (CMV) in people who have AIDS ( acquired immunodeficiency syndrome ). Cidofovir is for treating CMV only in people who have AIDS.
Cidofovir is not a cure for CMV and may not prevent vision changes.
Cidofovir may also be used for purposes not listed in this medication guide.
Indications
Cidofovir is an antiviral medicine that is used to treat an eye infection called cytomegalovirus retinitis (CMV) in people who have AIDS ( acquired immunodeficiency syndrome ). Cidofovir is for treating CMV only in people who have AIDS.
Cidofovir is not a cure for CMV and may not prevent vision changes.
Cidofovir may also be used for purposes not listed in this medication guide.
Contraindications
You should not be treated with cidofovir if you are allergic to it, or if you have:
moderate to severe kidney disease; or a history of severe allergic reaction to probenecid or sulfa drugs .
You should not receive cidofovir if you've used certain other medicines within 7 days before a cidofovir injection. Tell your doctor if you use any of the following:
blood pressure medicine; cancer medicine; injectable medications to treat osteoporosis or Paget's disease of bone; medication to prevent organ transplant rejection; medicines for infections; medicines to treat a bowel disorder; or some pain or arthritis medicines (including Advil, Motrin, and Aleve).
Tell your doctor if you have ever had:
kidney disease; diabetes; or pancreas problems.
Cidofovir can harm an unborn baby if the mother or the father is using cidofovir.
If you are a woman, do not use cidofovir if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 month after your last dose. If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using cidofovir.
Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Cidofovir may cause serious side effects. Call your doctor at once if you have:
vision changes, white or yellow patches on your eyes; kidney problems --swelling, rapid weight gain, little or no urinating, increased thirst, loss of appetite, constipation , pain in your side or lower back; low blood cell counts --fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or pancreatitis --severe pain in your upper stomach spreading to your back, nausea and vomiting.
Common side effects of cidofovir may include:
nausea, vomiting, diarrhea; pain, weakness; rash; headache; or hair loss .
While taking probenecid , you may have side effects such as:
nausea, vomiting; skin rash; fever, chills; or headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Cidofovir can harm your kidneys after only one or two doses. You should not receive cidofovir if you have used any of the following drugs within the past 7 days: certain medicines for infections, cancer, osteoporosis , organ transplant rejection, bowel disorders, high blood pressure , or pain or arthritis (including Advil, Motrin, and Aleve).
High Risk Groups
Cidofovir can harm your kidneys after only one or two doses. You should not receive cidofovir if you have used any of the following drugs within the past 7 days: certain medicines for infections, cancer, osteoporosis , organ transplant rejection, bowel disorders, high blood pressure , or pain or arthritis (including Advil, Motrin, and Aleve).
Adult Dosage
5 mg/kg (5 (5)) As recommended. IV — Adult induction: Once weekly for 2 consecutive weeks.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Many drugs can affect cidofovir, and some drugs should not be used within 7 days before you receive cidofovir. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible interactions are listed here.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.