Cinitapride
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Cinitapride is a new prokinetic agent. It is a substituted benzamide with 5-HT receptor antagonist and 5-HT- receptor agonist activity. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.
Indications
Cinitapride is primarily indicated in conditions like Constipation, Delayed gastric emptying, Gastro-esophageal reflux disease, Non-ulcer dyspepsia.
Contraindications
Cinitapride is contraindicated in conditions like Hypersensitivity to the drug,Hypersensitivity to any component of product.
Side Effects
The severe or irreversible adverse effects of Cinitapride, which give rise to further complications include Angioedema, Gynacomastia, Angioedema.The signs and symptoms that are produced after the acute overdosage of Cinitapride include Drowsiness, Confusion, Extrapyramidal effects.The symptomatic adverse reactions produced by Cinitapride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Diarrhea, Sedation, Extra pyramidal symptoms.
Warnings
Used with caution especially in the elderly because it enhances the action of acetylcholine. It should not be used in patients in whom an increase in gastrointestinal motility could be harmful, e.g. in patients with gastrointestinal hemorrhage, mechanical obstruction or perforation. Used with caution in patients with a history of dyskinesia induced by neuroleptics. Drowsiness may occur with the use of cinitapride and hence caution is to be exercised while driving and using machines. Do not take with alcohol since increased sedation may occur.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
1 to 1 mg (1 (1)) 8 hourly PO — Take 15 minutes before meal. The dose may be reduced, if required, depending on the patient’s age and symptoms.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Cinitapride was found.
Storage
Store Between 15°C-25°C. Protect from Moisture.
Available Brands in Pakistan
1 active brand listed alphabetically.
CIDINE
ActiveHIGHNOON LABORATORIES LTD.
DML: CIDINE
SyrupTabs
3 additional records are present but flagged "Unverified / Legacy" and not listed.