Clavulanic Acid

Clavulanic Acid is a ß lactamase inhibitor. Clavulanic Acid is structurally related to the penicillin and used in combination with penicillin antibiotic to treat variety of bacterial infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Clavulanic Acid is important to take the drug for the full time period as prescribed. If you discontinue the therapy it may result in ineffective treatment.

Clavulanic Acid is primarily indicated in conditions like Bacterial infections, Myeloablative therapy followed by bone marrow transplantation, Respiratory tract infections, Urinary tract infection.

Clavulanic Acid is contraindicated in conditions like Glandular fever, Penicillin hypersensitivity.

The severe or irreversible adverse effects of Clavulanic Acid, which give rise to further complications include Hypersensitivity reactions, Eosinophilia, Severe diarrhea, Hepatic cholestasis. Clavulanic Acid produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis. which are responsible for the discontinuation of Clavulanic Acid therapy. The signs and symptoms that are produced after the acute over dosage of Clavulanic Acid include Nausea, Vomiting. The symptomatic adverse reactions produced by Clavulanic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Fever, Maculopapular rash, Urticaria, Increase in serum transaminase.

Clavulanic acid should be used with caution in patients with other illnesses or any allergy especially to penicillin or other antibiotics. This medication should be used only if clearly needed during pregnancy or lactation.

Drug should not be given to Pregnant Mothers. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

125 mg (120 (125)) 12 hourly PO — Only in combination with either Amoxicillin or Ticarcillin.

No child dosage information is recorded for this medicine yet.

6 mg.kg (6 (6)) 6 hourly oral — 6 mg/kg (6 (6)) 6 hourly Intramuscular — 6 mg/kg (6 (6)) 6 hourly Intravenous —

No data regarding the interactions of Clavulanic Acid was found.

Inj (reconstituted susp) Store in refrigerator. Use within 10 days if kept at room temperature. Tab, Oral Susp, Dry Powder for Inj Store at room temperature, Below 25°C. Protect from Moisture.