Clopamide
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Clopamide is a diuretic reduces the absorption of electrolytes from renal tubule. It increases the urination. Clopamide is used in hypertension to lower the high blood pressure and to treat edema associated with heart failure.
Indications
Clopamide is primarily indicated in conditions like Congestive heart failure, Hepatic disease, Mild to moderate hypertension,
Contraindications
Clopamide is contraindicated in conditions like Gout, Maturity onset diabetes, Documented Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Clopamide, which give rise to further complications include Hypokalemia, Hyperglycemia, Precipitation of gout, Hyperglycemia. Clopamide produces potentially life-threatening effects which include Coronary insufficiency, Decreased BP, which are responsible for the discontinuation of Clopamide therapy. The symptomatic adverse reactions produced by Clopamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Gout, Renal failure, Hepatic failure.
Warnings
The drug should be used with extreme caution in diabetic patients because clopamide can worsen diabetic control, raising blood sugar level and may precipitate gout. It should be used with caution in combination with other antihypertensive drugs such as thiazide and loop diuretics, as it increases the urinary excretion of potassium and can cause hypokalemia, potassium supplements are used to treat hypokalemia.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.142 to 0.285 mg/kg (0.21 (0.2135)) 12 hourly PO — As Required
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Clopamide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbenoxolone (Na)LithiumNateglinideConcurrent use may reduce the hypoglycemic action of Nateglinide.Tetracycline (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, at room temperature, Below 30°C.
Available Brands in Pakistan
No brands are recorded for this generic.