Question 1

What is Cloxacillin used for?

Accepted Answer

It is used to treat bacterial infections.

Question 2

What is the adult dose of Cloxacillin?

Accepted Answer

250 mg (250 (250)) 6 hourly IM —  
500 mg (500 (500)) 6 hourly IV (slow) — Over 3-4 min.
500 mg (500 (500)) 24 hourly Intra Peritoneal —  
500 mg (500 (500)) 6 hourly PO —

Question 3

What is the paediatric dose of Cloxacillin?

Accepted Answer

12.5 to 25 mg/kg (19 (18.75)) 6 hourly Oral — -
12.5 to 25 mg/kg (19 (18.75)) 6 hourly Slow IV — -

Question 4

What are the side effects of Cloxacillin?

Accepted Answer

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your
      doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Signs of an allergic reaction, like rash ; hives; itching ; red, swollen, blistered, or peeling skin with or without fever ; wheezing ;
      tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue,
      or throat. Sneezing. Very upset stomach or throwing up. Severe diarrhea , even after drug is stopped. Any unexplained bruising or bleeding. Seizures . For females, vaginal yeast infection . Report itching or discharge.

Question 5

Who should not take Cloxacillin?

Accepted Answer

Cloxacillin is contraindicated in conditions like Hypersensitivity.

Question 6

What does Cloxacillin interact with?

Accepted Answer

Cloxacillin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementChloramphenicolChloramphenicol inhibit the effect of cloxacillin by inhibiting cellular protein synthesis and change bacteria into static one thus reducing the effectiveness of carbenicillin.ModerateCombination must be avoided. If necessary then cloxacillin administered several hours before chloramphenicol and closely observed.ProbenecidTetracycline (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Cloxacillin

Available Brands in Pakistan

AMCLOX

BOSCHOCLOX

CILICLOX

CLOXACILLIN

CLOXCIN-250

CLOXCIN-500

WERICLOX