Co-Fluampicil
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Co-Fluampicil is a mixture of equal parts by mass of flucloxacillin and ampicillin, used to produce a wider spectrum of activity. Ampicillin is a beta-lactam antibiotic active against certain gram +ive and gram -ive organisms, but is inactivated by penicillinases. Flucloxacillin, however, is a penicillinase-resistant antibiotic and thus effective in infections caused by penicillin-resistant staphylococci.
Indications
Co-Fluampicil is primarily indicated in conditions like Infections in the chest, ear, throat, skin and soft tissue, Septic abortion, puerperal fever.
Contraindications
Co-Fluampicil is contraindicated in conditions like Penicillin hypersensitivity.
Side Effects
The symptomatic adverse reactions produced by Co-Fluampicil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Fever, Rashes, Urticaria, Hemolytic anemia, Thrombocytopenia, Neutropenia, Hypersensitivity reactions, Cholestatic Jaundice, Angioedema, Joint pain, Hepatitis, Anaphylaxis, Interstitial nephritis, Convulsions (especially with high doses or in severe renal impairment), Antibiotic-associated colitis.
Warnings
Co-Fluampicil should be used with caution in patients with history of allergy; erythematous rash common in glandular fever; cytomegalovirus infections; acute or chronic lymphocytic leukemia; renal impairment (reduce dose if severe); porphyria; cholestatic jaundice. CSM has advised that cholestatic jaundice may occur up to several weeks after treatment with Co-Fluampicil has been stopped. Administration for more than 2 weeks and increasing age are risk factors.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
250 mg/day (250 (250)) 6 hourly PO — Should be taken 1 hour before meal.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Co-Fluampicil was found.
Storage
No storage information is recorded for this medicine yet.
Available Brands in Pakistan
No brands are recorded for this generic.