Cocaine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Cocaine is a local anesthetic. It is applied to certain areas of the body (for example, the nose, mouth, or throat) to cause loss of feeling or numbness. This allows certain kinds of procedures or surgery to be done without causing pain.
Cocaine can cause psychological dependence (a strong desire to continue using the medicine because of the "high" feeling it produces). This may lead to cocaine abuse (more frequent use and/or use of larger amounts of cocaine) and to an increased chance of serious side effects. Cocaine abuse has caused death from heart or breathing failure.
Use of cocaine as a local anesthetic for an examination or surgery is not likely to cause psychological dependence or other serious side effects. However, if cocaine is absorbed into the body too quickly, serious side effects can occur. Also, some people are especially sensitive to the effects of cocaine. Unwanted effects may occur in these people even with small amounts of the medicine. Before receiving cocaine as a local anesthetic, you should discuss its use with your doctor.
Cocaine is applied only by or under the immediate supervision of your doctor.
Indications
Cocaine is a local anesthetic. It is applied to certain areas of the body (for example, the nose, mouth, or throat) to cause loss of feeling or numbness. This allows certain kinds of procedures or surgery to be done without causing pain.
Cocaine can cause psychological dependence (a strong desire to continue using the medicine because of the "high" feeling it produces). This may lead to cocaine abuse (more frequent use and/or use of larger amounts of cocaine) and to an increased chance of serious side effects. Cocaine abuse has caused death from heart or breathing failure.
Use of cocaine as a local anesthetic for an examination or surgery is not likely to cause psychological dependence or other serious side effects. However, if cocaine is absorbed into the body too quickly, serious side effects can occur. Also, some people are especially sensitive to the effects of cocaine. Unwanted effects may occur in these people even with small amounts of the medicine. Before receiving cocaine as a local anesthetic, you should discuss its use with your doctor.
Cocaine is applied only by or under the immediate supervision of your doctor.
Contraindications
Cocaine is contraindicated in conditions like Ophthalmologic anesthesia. Hypersensitivity to cocaine, other ester type local anesthetics, or other product ingredients.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Less common or Rare
Abdominal or stomach pain chills confusion dizziness or lightheadedness excitement, nervousness, restlessness, or any mood or mental changes fast or irregular heartbeat general feeling of discomfort or illness hallucinations or seeing, hearing, or feeling things that are not there headache (sudden) increased sweating nausea
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Loss of sense of taste or smell (after use in the nose or mouth)
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Available Dosage Forms:
Solution
Therapeutic Class: Anesthetic, Local
Chemical Class: Amino Ester
Warnings
Avoid cocaine in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitate, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided. Cocaine should not be applied to damage mucosa. Ophthalmic preparation of cocaine should not be applied to the eyes for prolonged period, because cause the damage of cornea. Patients receiving cocaine for surface anesthesia should be monitored for possible cardiovascular effects. It is not recommended for use during pregnancy.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
5 to 20 % (12 (12.5)) As recommended. Topical — As Required
Child Dosage
( ) — Not recommended in this age group
Neonatal Dosage
( ) — Not recommended in this age group
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Dihydroergotamine Phenelzine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Alfentanil Almotriptan Amifampridine Amitriptyline Amoxapine Amphetamine Benzhydrocodone Benzphetamine Bupivacaine Bupivacaine Liposome Buprenorphine Bupropion Butorphanol Citalopram Codeine Desvenlafaxine Dextroamphetamine Dextromethorphan Dihydrocodeine Dolasetron Donepezil Duloxetine Escitalopram Fenfluramine Fentanyl Fluoxetine Fluvoxamine Gepirone Granisetron Hyaluronidase Hydrocodone Hydromorphone Hydroxyamphetamine Hydroxytryptophan Iobenguane I 123 Iobenguane I 131 Lasmiditan Levomilnacipran Levorphanol Lisdexamfetamine Lithium Lorcaserin Meperidine Metaxalone Methadone Methamphetamine Methylene Blue Milnacipran Mirtazapine Morphine Morphine Sulfate Liposome Nalbuphine Ondansetron Oxycodone Oxymorphone Palonosetron Paroxetine Pentazocine Remifentanil Sertraline St John's Wort Sufentanil Tapentadol Tramadol Trazodone Vilazodone Vortioxetine Ziprasidone
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Cannabis
Storage
Topical Soln, Nasal Spray Store Below 25°C. Protect from Sunlight.
Available Brands in Pakistan
No brands are recorded for this generic.
