Corticotropin

Corticotropin is a hormone that is used to treat many conditions such as psoriasis, Steven Johnson syndrome, psoriatic or rheumatoid arthritis , ankylosing spondylitis , lupus, polymyositis, severe allergic reactions , symptomatic sarcoidosis, and inflammatory conditions of the eyes. Corticotropin is also used to treat acute episodes of multiple sclerosis in adults. Corticotropin is also used to treat infantile spasms in children younger than 2 years old. Corticotropin can reduce the symptoms of an illness, but it is not a cure for these conditions. Corticotropin is also not expected to slow the progress of any disease. Corticotropin may also be used for purposes not listed in this medication guide.

Corticotropin is a hormone that is used to treat many conditions such as psoriasis, Steven Johnson syndrome, psoriatic or rheumatoid arthritis , ankylosing spondylitis , lupus, polymyositis, severe allergic reactions , symptomatic sarcoidosis, and inflammatory conditions of the eyes. Corticotropin is also used to treat acute episodes of multiple sclerosis in adults. Corticotropin is also used to treat infantile spasms in children younger than 2 years old. Corticotropin can reduce the symptoms of an illness, but it is not a cure for these conditions. Corticotropin is also not expected to slow the progress of any disease. Corticotropin may also be used for purposes not listed in this medication guide.

You should not be treated with corticotropin if you are allergic to it, or if you have: infection caused by fungus; herpes infection of the eyes; untreated or uncontrolled high blood pressure ; scleroderma; osteoporosis ; problems with adrenal gland; a stomach ulcer ; congestive heart failure ; an allergy to pork products; recent surgery; or if you are scheduled to receive a live vaccine. Corticotropin should not be used in children under 2 years of age if they had certain infections passed from the mother during pregnancy or childbirth. Corticotropin may make it easier for you to get an infection or worsening an infection you already have. Tell your doctor about any illness or infection you had within the past several weeks. Tell your doctor if you have or have ever had: an active or recent infection (in you or a family member); high blood pressure, heart problems; a thyroid disorder; diabetes; seizure (convulsions); tuberculosis (or if you have close contact with someone who has tuberculosis); a nerve-muscle disorder, such as myasthenia gravis ; a perforation (a hole or tear) in your esophagus, stomach, or intestines; diverticulitis ; glaucoma or cataracts; mental illness or psychosis; a stomach or intestinal disorder, stomach bleeding; cirrhosis or other liver disease ; or kidney disease. Tell your doctor if you or a family member recently received a vaccine or are scheduled to receive a vaccine. Corticotropin may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Ask a doctor if it is safe to breastfeed while using corticotropin. Do not give this medicine to a child without medical advice.

Get emergency medical help if you have signs of an allergic reaction : hives, difficult breathing, swelling of your face, lips, tongue, or throat. Corticotropin may cause serious side effects. Call your doctor at once if you have: unusual changes in mood or behavior; blurred vision, eye pain or redness, seeing halos around lights; a seizure; sudden pain or trouble moving your hip, wrist, or back; high blood pressure --severe headache, blurred vision, pounding in your neck or ears; new or worsening signs of infection --fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; decreased or increased adrenal gland hormones --changes in weight or appetite, tiredness, muscle weakness, skin discoloration, thinning skin, increased body hair, menstrual changes, loss of appetite, stomach pain; new or worsening symptoms of high blood sugar --increased thirst, increased urination, dry mouth, fruity breath odor; low blood potassium --leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; fluid retention -- shortness of breath (even while lying down), swelling, rapid weight gain (especially in your face and midsection); signs of eye infection --swelling, redness, severe discomfort, crusting or drainage; or stomach or intestinal problems --fever, severe stomach pain, change in bowel habits, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. Corticotropin can affect growth and appetite. Tell your doctor if you notice changes in weight or appetite, or if your child is not growing at a normal rate while using corticotropin. Common side effects of corticotropin may include: pain, bruising, swelling, or irritation where the medicine was injected; high blood sugar levels, seizures (convulsions), increased blood pressure; swelling in your hands or feet, puffiness in your face; unusual changes in mood or behavior, irritability; tiredness, lack of energy, sleep problems (insomnia), dolor de cabeza; o fever, infections. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You may get infections more easily. Call your doctor if you have any signs of infection (fever, cough, skin sores, painful urination).

You may get infections more easily. Call your doctor if you have any signs of infection (fever, cough, skin sores, painful urination).

40 to 80 units (60 (60)) As recommended. IM/SC — Repository injection: should be injected every 24-72 hours. 80 to 120 units/day (100 (100)) As recommended. IM — Acute Exacerbations of Multiple Sclerosis: should be injected for 2 to 3 weeks.

40 to 80 (60 (60)) As recommended. I/M or S.C — Over 2 years of age. every 24 to 72 hours.

75 unit/m2 (75 (75)) As recommended. I/M — under 2 year of age. Twice daily over a 2 weeks period, then gradually taperod over adrenal insuffication.

Tell your doctor about all your other medicines, especially: aspirin; or a diuretic or "water pill". This list is not complete. Other drugs may affect corticotropin, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.

Inj (reconstituted soln) Store at room temperature or refrigerator. Use within 24 hrs if kept at room temperature. Susp Store in a well closed container, Below 25°C. Protect from Sunlight.