Medicines/Generics/Desloratadine

Desloratadine

Generic medicine reference

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Overview

Desloratadine is an active metabolite of loratadine, a non-sedating antihistamine. It causes less sedation and psychomotor impairment than the older antihistamines because it penetrates the blood brain barrier only to a slight extent. Desloratadine is used for the symptomatic relief of allergic conditions such as urticaria and hay fever.

Indications

Desloratadine is primarily indicated in conditions like Perennial rhinitis, Urticaria, and can also be given in adjunctive therapy as an alternative drug of choice in Seasonal allergic rhinitis, Chronic idiopathic urticaria.

Contraindications

Desloratadine

Side Effects

Desloratadine produces potentially life-threatening effects which include Arrhythmias, Anaphylaxis, Angioedema, Extrapyramidal symptoms. which are responsible for the discontinuation of Desloratadine therapy. The symptomatic adverse reactions produced by Desloratadine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Fatigue, Myalgia, Palpitation, Dry mouth, Blurred vision, Urinary retention, Pharyngitis, GI disturbance, Cough, Fever, Diarrhea, Somnolence, Erythema, Macupopular rash, Dysmenorrhea, Epistaxis, Bronchitis.

Warnings

Antihistamines (e.g. Desloratadine) should be used with caution in prostatic hypertrophy, urinary retention, epilepsy, glaucoma, Pyloroduodenal obstruction, hepatic disease, dose reduction may be necessary in renal impairment. Children and the elderly are more susceptible to side-effects.

High Risk Groups

Drug should not be given to Pediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Adult Dosage

5 mg (5 (5)) 24 hourly PO —

Child Dosage

1.25 1 (1.2 (1.25)) As recommended. for 12 months to 5 year. — 2.5 mg (2.5 (2.5)) 24 hourly for 6 to 11 years —

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

No data regarding the interactions of Desloratadine was found.

Storage

No storage information is recorded for this medicine yet.

Available Brands in Pakistan

36 active brands listed alphabetically.

Desloratadine

Available Brands in Pakistan

ALENOR

ALENOR REDITAB

ALORET

DASTAK

DELERGIC

DESCOVER

DESGEN

DESGOOD

DESLET

DESLO

DESLOR

DESLORAT

DESLOREAL

DESLORT

DESOLINE

DESORA

DESTAZINE

DESTINA

DESTRA

DESTREX

DICTRIN

DINESTIN

DISDINE

D-LOR

D-LORAATA

DULIN

E-DIN

HISTANIL D

JARDIN-D

LARINEX

LOTODINE

NEO-ANTIAL

REETAG

RETORET

SELORA

SLORIT