Desvenlafaxine
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Desvenlafaxine is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant.
Desvenlafaxine is used to treat major depressive disorder .
Desvenlafaxine may also be used for purposes not listed in this medication guide.
Indications
Desvenlafaxine is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant.
Desvenlafaxine is used to treat major depressive disorder .
Desvenlafaxine may also be used for purposes not listed in this medication guide.
Contraindications
You should not use desvenlafaxine if you are allergic to desvenlafaxine or venlafaxine (Effexor).
Do not use desvenlafaxine within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid , linezolid, methylene blue injection, phenelzine , or tranylcypromine . A dangerous drug interaction could occur.
Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products , or medicine for depression, mental illness, Parkinson's disease , migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with desvenlafaxine could cause a serious condition called serotonin syndrome.
Tell your doctor if you have ever had:
heart disease , high blood pressure , high cholesterol , or a stroke; bipolar disorder ( manic depression ); depression, suicidal thoughts; liver or kidney disease; glaucoma; seizures or epilepsy; sexual problems; lung or breathing problems; a bleeding or blood clotting disorder; or low levels of sodium in your blood.
People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior.
Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop desvenlafaxine without asking your doctor.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of desvenlafaxine on the baby.
Ask a doctor if it is safe to breastfeed while using this medicine.
Not approved for use by anyone younger than 18 years old.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks , trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself.
Desvenlafaxine may cause serious side effects. Call your doctor at once if you have:
a seizure; easy bruising or bleeding (nosebleeds, bleeding gums), blood in your urine or stools, coughing up blood; blurred vision, eye pain or swelling, or seeing halos around lights; cough, chest discomfort, trouble breathing; or low blood sodium --headache, confusion, problems with thinking or memory, weakness, feeling unsteady.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate , muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Common side effects of desvenlafaxine may include:
dizziness, drowsiness, anxiety; increased sweating; nausea, decreased appetite, constipation ; sleep problems (insomnia); or decreased sex drive, impotence, or difficulty having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide.
Do not stop using desvenlafaxine without first asking your doctor.
High Risk Groups
People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide.
Do not stop using desvenlafaxine without first asking your doctor.
Adult Dosage
Scraped Dose — Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take desvenlafaxine with water at the same time each day, with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
Your symptoms may not improve for several weeks.
Your blood pressure will need to be checked often.
Tell your doctor if you have any changes in sexual function, such as loss of interest in sex, trouble having an orgasm, or (in men) problems with erections or ejaculation. Some sexual problems can be treated.
Do not stop using desvenlafaxine suddenly , or you could have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine.
Part of a tablet shell may appear in your stool but this will not make the medicine less effective.
Store at room temperature away from moisture and heat.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Using desvenlafaxine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially a blood thinner (warfarin, Coumadin, Jantoven) or other medicine used to prevents blood clots.
Other drugs may affect desvenlafaxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Storage
Tablet Store Between 20°C-25°C. Refrigeration and Freezing is not recommended. Protect from Sunlight.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.
