Dexamphetamine (Sulphate)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Dexamphetamine (Sulphate) used in the treatment of narcolepsy and as an adjunct in the management of hyperactivity disorders in children (above the age of 6 years).
Indications
Dexamphetamine (Sulphate) is primarily indicated in conditions like Attention deficit disorders, Narcolepsy.
Contraindications
Dexamphetamine (Sulphate) is contraindicated in conditions like Angina, Diabetes mellitus, Glaucoma, Hypertension, Hyperthyroidism, Insomnia, Anorexia, Psychopathic personality, Gille de la tourette syndrome, Cardiovascular disease, Dyskinesia.
Side Effects
The severe or irreversible adverse effects of Dexamphetamine (Sulphate), which give rise to further complications include Hallucinations, Hypertension, Arrhythmia. Dexamphetamine (Sulphate) produces potentially life-threatening effects which include Intracranial hemorrhages, Acute Renal Failure, Intracerebral bleeding, Acute renal failure, which are responsible for the discontinuation of Dexamphetamine (Sulphate) therapy .The symptomatic adverse reactions produced by Dexamphetamine (Sulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Irritability, Anorexia, Palpitation, Tachycardia, Insomnia, Nervousness, Abdominal pain, Sweating, Sleep disturbances, Blurred vision, Weight Loss, Dysphoria, Mydriasis.
Warnings
Dexamphetamine should not be used in patients with cardiovascular disease including moderate to severe hypertension, hyperthyroidism, glaucoma, hyper excitability, agitated state, history of drug abuse. It is not recommended to use during pregnancy or lactation. It should be used with caution in patients with mild hypertension, impaired kidney function, epilepsy or unstable personality. Weight and height in children should be monitored as growth retardation may occur. Prolonged high dose may need gradual withdrawal as abrupt withdrawal may produce fatigue or mental depression.
High Risk Groups
Drug should not be given to Pediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.024 to 0.285 mg/kg (0.15 (0.1545)) 8 hourly PO — As Required
Child Dosage
5 mg (5 (5)) As recommended. Hyperactivity dose may be increased by 5mg at weekly intervals to upper limity of 20mg & 40mg in chi —
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Dexamphetamine (Sulphate) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAlcoholChlorpromazine (HCl)Dipipanone (HCl)EthosuximideGuanethidineHaloperidolLithiumMetoprolol (Tartrate)MorphineMorphinePapaveretumPhenobarbitonePhenytoin (Na)PrazosinPropranolol (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.