Dexfenfluramine (HCl)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Dexfenfluramine (HCl) is a selective 5-HT agonist effective in reducing obesity. It is a serotonergic anorectic drug which reduces appetite by increasing the amount of extracellular serotonin in the brain.
Indications
Dexfenfluramine (HCl) is primarily indicated in conditions like Eating behavior disorders, Obesity.
Contraindications
Dexfenfluramine (HCl) is contraindicated in conditions like Glaucoma.
Side Effects
Dexfenfluramine (HCl) produces potentially life-threatening effects which include Valvular heart defects, Pulmonary hypertension. which are responsible for the discontinuation of Dexfenfluramine (HCl) therapy. The signs and symptoms that are produced after the acute over dosage of Dexfenfluramine (HCl) include Tachycardia, Convulsions, Restlessness, Ventricular arrhythmias, Excitement. The symptomatic adverse reactions produced by Dexfenfluramine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Fatigue, Nausea, Vomiting, Constipation, Dry mouth, Polyuria, Xerostomia.
Warnings
Dexfenfluramine should be avoided in patients with pulmonary hypertension, past or current history of cardiovascular or cerebrovascular disease, psychiatric disease, glaucoma, epilepsy, history of drug abuse. It should be used with extreme caution in elderly or during pregnancy or lactation. Avoid abrupt withdrawal. Patient should observe caution while driving or performing other task requiring alertness because it may produce dizziness, extreme fatigue and depression. It should be used with caution and monitor blood pressure in patients with mild hypertension. Dose titration and dose discontinuance may be necessary in epileptic patients.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
0.214 mg/kg (0.21 (0.214)) 12 hourly PO — For Max 3 Months
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Dexfenfluramine (HCl) was found.
Storage
Caps Store at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.