Dexibuprofen
Generic medicine reference
Overview
Dexibuprofen [S(+)-Ibuprofen] is considered as the pharmacologically active enantiomer of racemic Ibuprofen. Like racemic Ibuprofen, Dexibuprofen is a non-steroidal antiinflammatory drug with analgesic action. Like Ibuprofen, Dexibuprofen acts by inhibiting prostaglandin synthesis.
Indications
Dexibuprofen is primarily indicated in conditions like Dental pain, Mild to moderate pain, Osteoarthritis, and can also be given in adjunctive therapy as an alternative drug of choice in Dysmenorrhoea.
Contraindications
Dexibuprofen is contraindicated in conditions like Ulcerative colitis,Impaired hepatic function,Haemorrhagic diathesis,Crohn's disease,Severe renal impairment,Gastric ulcer,Coagulation disorder,Bleeding disorders,Hypersensitivity to the drug.
Side Effects
The severe or irreversible adverse effects of Dexibuprofen, which give rise to further complications include Tinnitus, Bronchospasm, Bronchospasm.The symptomatic adverse reactions produced by Dexibuprofen are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Nausea, Vomiting, Diarrhea, Abdominal pain, Dyspepsia, dyspepsia.
Warnings
Symptoms or history of gastro-intestinal disease, asthma, impaired hepatic, cardiac or renal function. NSAID may mask infections or temporarily inhibit platelet aggregation. In late pregnancy, as with other NSAIDs, it should be avoided as it may cause premature closure of ductus arteriosus. Dexibuprofen should be used with caution in nursing mothers. Patients with mild to moderate hepatic dysfunction should start therapy at reduced doses and be closely monitored. Dexibuprofen should not be used in patients with severe hepatic dysfunction. The initial dosage should be reduced in patients with mild to moderate impaired renal function. Dexibuprofen should not be used in patients with severe renal dysfunction.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
200 to 400 mg (300 (300)) 8 hourly PO — For mild to moderate pain:
300 to 300 mg (300 (300)) 8 hourly PO — For acute symptoms of osteoarthritis, the dose may be increased up to 400mg tablet 3 times a day.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Dexibuprofen was found.
Storage
Tablet Store Between 15°C-30°C. Protect from Sunlight, Moisture and Heat.
Available Brands in Pakistan
10 active brands listed alphabetically.
BRUTEK
ActiveGENOME PHARMACEUTICALS (PVT) LTD
DML: BRUTEK
Tabs
DEXIBU
ActiveOPAL LABORATORIES (PVT) LTD.
DML: DEXIBU
Tabs
DEXIFEN
ActiveICI PAKISTAN LTD.
DML: DEXIFEN
Tabs
Dexyken
ActiveKANEL PHARMACEUTICALS
DML: Dexyken
Tabs
Hifen-X
ActiveHELIX PHARMA (PRIVATE) LIMITED
DML: Hifen-X
SuspTabs
MEDIPRUFEN
ActiveMEDIPAK LIMITED
DML: MEDIPRUFEN
Tabs
TERCICA
ActiveSAMI PHARMACEUTICALS (PVT) LTD.
DML: TERCICA
SuspTabs
VANIT
ActiveGETZ PHARMA PAKISTAN (PVT) LTD.
DML: VANIT
Tabs
XIB
ActiveS.J. & G. FAZUL ELLAHIE (PVT) LTD.
DML: XIB
SuspTabs
ZIBUFEN
ActiveGLOBAL BRANDS DISTRIBUTORS
DML: ZIBUFEN
SuspTabs
For educational purposes only. Check current guidelines and consult a qualified healthcare professional before making clinical decisions.