Medicines/Generics/Diclofenac (K)

Diclofenac (K)

Generic medicine reference

Not yet clinically reviewed

This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.

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Overview

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation. Diclofenac is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis . Voltaren is also indicated for the treatment of ankylosing spondylitis. The Cataflam brand of this medicine is also used to treat menstrual cramps. Diclofenac powder (Cambia) is used to treat a migraine headache attack. Cambia will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Indications

Contraindications

Diclofenac can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diclofenac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not use diclofenac if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Do not use Cambia to treat a cluster headache. Do not use Zipsor if you are allergic to beef or beef protein. To make sure this medicine is safe for you, tell your doctor if you have: heart disease, high blood pressure ; ulcers or bleeding in your stomach; asthma; liver or kidney disease; or if you smoke. Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. If you are pregnant, you should not take diclofenac unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Diclofenac is not approved for use by anyone younger than 18 years old.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to diclofenac ( hives , difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling). Stop using diclofenac and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Stop using this medicine and call your doctor at once if you have: the first sign of any skin rash, no matter how mild; flu-like symptoms; heart problems - swelling, rapid weight gain, feeling short of breath; kidney problems - little or no urinating, painful or difficult urination, swelling in your arms or legs, feeling tired or short of breath; liver problems - nausea, diarrhea, stomach pain (upper right side), tiredness, itching, dark urine, jaundice (yellowing of the skin or eyes); or signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. Common diclofenac side effects may include: indigestion, gas, nausea , vomiting , stomach pain ; diarrhea , constipation; headache, dizziness , drowsiness; abnormal lab tests; itching, sweating; stuffy nose; increased blood pressure; or swelling or pain in your arms or legs. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not use diclofenac if you have a history of allergic reaction to aspirin or NSAIDs (non-steroidal anti-inflammatory drugs). Diclofenac can increase your risk of fatal heart attack or stroke , especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diclofenac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

High Risk Groups

Adult Dosage

50 mg (50 (50)) 8 hourly PO — Scraped Dose — Take diclofenac exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition. Different brands of diclofenac contain different amounts of diclofenac, and may have different uses . If you switch brands, your dose needs may change. Follow your doctor's instructions about how much medicine to take. Ask your pharmacist if you have any questions about the brand you receive at the pharmacy. Swallow the tablet whole and do not crush, chew, or break it. Take Zorvolex on an empty stomach, at least 1 hour before or 2 hours after a meal. Dissolve the powder form of this medicine (Cambia) with 1 to 2 ounces of water. Do not use any other type of liquid. Stir this mixture and drink all of it right away. Cambia works best if you take it on an empty stomach. Call your doctor if your headache does not completely go away after taking Cambia. If you use diclofenac long-term, you may need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Child Dosage

0.166 to 0.666 mg/kg (0.42 (0.416)) 8 hourly Oral —

Neonatal Dosage

No neonatal dosage information is recorded for this medicine yet.

Drug Interactions

Ask your doctor before using diclofenac if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Tell your doctor about all your other medicines, especially: heart or blood pressure medication, including a diuretic or "water pill"; other forms of diclofenac ( Arthrotec , Flector , Pennsaid , Solaraze, Voltaren Gel ); a blood thinner - warfarin , Coumadin , Jantoven ; or other NSAIDs - aspirin, ibuprofen ( Advil , Motrin ), naproxen ( Aleve ), celecoxib ( Celebrex ), indomethacin , meloxicam , and others. This list is not complete. Other drugs may interact with diclofenac, including prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible drug interactions are listed here.

Storage

Inj, Tab, Eye Drops Store at room temperature. Do not Freeze. Protect from Sunlight.

Available Brands in Pakistan

130 active brands listed alphabetically.

Diclofenac (K)

Available Brands in Pakistan

ALFAKALIUM

AMDIK

ANDIC-K

ANTIFLAM

ANTI-PAIN

ARDI-K

ARIFLAM

ARTHOPOT

ARTIMOV-K

Avorek

BEFLAM

BIODIC-P

CAFLAM

CATAFEN

CAVERON

CLODIUM-K

CLONAP

CLOP

CLO-TASIUM

DARDNIL

DECTIL

DEFLAM

DENUM-K

DETAFLAM

DICBRO

DICFIN

DICLODYN K

DICLOKALIUM

DICLOMED

DICLO-P

DICLOREP

DICLOTUS K

DICLOVIS K

DICLOWAN-P

DICLOWAN-QA

DICLOX PLUS

DICLOYAN-P

DICOWISE K

DIC-P

DICPOT

DIFENE

DIFSOM-P

DINAK

DI-POT

DOLOCALM

DOLO-K

DORBID

DOSIUM

DYNA-K

ENGROL

EPLOPOT

FAPA

FASTAID PLUS

FENBAR

FENDIC

FENIK K

FEN-K

FRENDIK-P

FRODIC-P

GENEK-75

GLIF-K

HEUMATIC-K

HI-NIL

HONDIC K

JFENAC-P

KAFENAC

KALFEN

KANIC

KEMIPAN

KEMIPAN PLUS

KENAC

KERWEL

KETAGESIC

KETAWIN

KEYGESIC

KLIC-F

KLODIC

KOMFORT