Dienoestrol
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Dienoestrol is a synthetic sex hormone. Dienoestrol is used to treat symptoms associated with menopause and for the suppression of lactation. Structurally similar to diethylstilibestestrol.
Indications
Dienoestrol is primarily indicated in conditions like Atrophic vaginitis, Senile vaginitis, Vulvar squamous hyperplasia, and can also be given in adjunctive therapy as an alternative drug of choice in estrogen deficiency.
Contraindications
Dienoestrol is contraindicated in conditions like Pregnancy, Endometrial hyperplasia, Hypersensitivity to the drug.
Side Effects
The severe or irreversible adverse effects of Dienoestrol, which give rise to further complications include Gall bladder disease. Dienoestrol produces potentially life-threatening effects which include Hypercalcemia, Breast cancer, Hepatic adenoma, Endometrial carcinoma, Thromboembolic disease, Hypercalcemia. which are responsible for the discontinuation of Dienoestrol therapy. The symptomatic adverse reactions produced by Dienoestrol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Jaundice, GI upset, Weight gain, Elevated blood pressure, Hypersensitivity reactions, Hypersensitivity of lower vagina (vulva), Painful stimulation of breast, Endometrial bleeding, Changes in LFT, Salt retention, Water retention.
Warnings
Avoid use during pregnancy or lactation and in children. It should not be used in case of damage to latex condoms and diaphragms.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates. If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Adult Dosage
5 mg (5 (5)) As recommended. Intra Vaginal — Maint. on alternate days, as required
5000 to 10000 mg (7500 (7500)) 24 hourly Intra Vaginal — Initially for 2 Weeks
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
No data regarding the interactions of Dienoestrol was found.
Storage
Cream Store at room temperature.
Available Brands in Pakistan
No brands are recorded for this generic.