Diflunisal
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat mild to moderate pain, osteoarthritis , or rheumatoid arthritis .
Diflunisal may also be used for purposes not listed in this medication guide.
Indications
Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat mild to moderate pain, osteoarthritis , or rheumatoid arthritis .
Diflunisal may also be used for purposes not listed in this medication guide.
Contraindications
Diflunisal can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Diflunisal may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using diflunisal, especially in older adults.
You should not use diflunisal if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Tell your doctor if you have ever had:
heart disease , high blood pressure , high cholesterol , diabetes, or if you smoke; a heart attack , stroke, or blood clot; stomach ulcers or bleeding; asthma; fluid retention ; liver or kidney disease; or if you take aspirin to prevent heart attack or stroke.
If you are pregnant, you should not take diflunisal unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
You should not breastfeed while using diflunisal.
Diflunisal is not approved for use by anyone younger than 12 years old. Ask a doctor before giving this medicine to a child or teenager with a fever, flu symptoms, or chicken pox.
Side Effects
Get emergency medical help if you have signs of an allergic reaction (hives, runny or stuffy nose, wheezing, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, swelling in your legs, feeling short of breath.
Diflunisal may cause serious side effects. Stop using diflunisal and call your doctor at once if you have:
changes in your vision; any skin rash, no matter how mild; shortness of breath (even with mild exertion); swelling or rapid weight gain; signs of stomach bleeding --bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems --nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); kidney problems --little or no urination, swelling in your feet or ankles, feeling tired; or low red blood cells (anemia) --pale skin, unusual tiredness, feeling light-headed, cold hands and feet.
Common side effects of diflunisal may include:
nausea, vomiting, stomach pain, indigestion; diarrhea, constipation , gas; dizziness, drowsiness, headache, tired feeling; rash; or ringing in your ears.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Diflunisal can increase your risk of fatal heart attack or stroke. Do not use diflunisal just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diflunisal may also cause stomach or intestinal bleeding, which can be fatal.
High Risk Groups
Diflunisal can increase your risk of fatal heart attack or stroke. Do not use diflunisal just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diflunisal may also cause stomach or intestinal bleeding, which can be fatal.
Adult Dosage
3.571 to 7.143 mg/kg (5.4 (5.357)) 12 hourly PO — Maintenance, As Required
7.143 mg/kg (7.1 (7.143)) As recommended. PO — Initially for Once
Scraped Dose — Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.
Swallow the tablet whole and do not crush, chew, or break it.
If you use diflunisal long-term, you may need frequent medical tests.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using diflunisal.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Ask your doctor before using diflunisal if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.
Tell your doctor about all your other medicines, especially:
acetaminophen (Tylenol); cyclosporine ; lithium; methotrexate ; a blood thinner (warfarin, Coumadin, Jantoven); heart or blood pressure medication, including a diuretic or "water pill"; or steroid medicine (such as prednisone ).
This list is not complete. Other drugs may affect diflunisal, including prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible drug interactions are listed here.
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No active brands are currently recorded for this generic.
1 record is present but flagged "Unverified / Legacy" and excluded.
