Digoxin
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.
Digoxin is used to treat heart failure .
Digoxin is also used to treat atrial fibrillation , a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).
Indications
Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.
Digoxin is used to treat heart failure .
Digoxin is also used to treat atrial fibrillation , a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).
Contraindications
You should not use digoxin if you are allergic to it, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).
To make sure digoxin is safe for you, tell your doctor if you have ever had:
a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker); a heart attack ; slow heartbeats that have caused you to faint; Wolff-Parkinson-White Syndrome (sudden fast heartbeats); kidney disease; an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood); a thyroid disorder; or if you have recently been sick with vomiting or diarrhea .
Tell your doctor if you are pregnant. It is not known whether digoxin will harm an unborn baby. However, having heart failure or atrial fibrillation during pregnancy may cause complications such as premature birth or low birth weight, or risk of death in both mother and baby. The benefit of treating heart problems with digoxin may outweigh any risks to the baby.
It may not be safe to breast-feed while using digoxin. Ask your doctor about any risk.
Side Effects
Get emergency medical help if you have signs of an allergic reaction to digoxin: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
nausea, vomiting, diarrhea, stomach pain; fast, slow, or uneven heart rate; a light-headed feeling, like you might pass out; bloody or black, tarry stools; confusion, weakness, hallucinations, unusual thoughts or behavior; breast swelling or tenderness; blurred vision, yellowed vision; or (in babies or children) stomach pain, weight loss , growth delay, behavior changes.
Serious side effects may be more likely in older adults and those who are ill or debilitated.
Common digoxin side effects may include:
nausea, diarrhea; feeling weak or dizzy; headache , weakness, anxiety , depression ; or rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
You should not use digoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).
High Risk Groups
You should not use digoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).
Adult Dosage
125 to 250 ug (190 (187.5)) 24 hourly PO — Maintenance, As Required
750 to 1500 ug (1100 (1125)) As recommended. PO — In div.doses.
Child Dosage
25 to 35 ug/kg (30 (30)) As recommended. Intra Musular — Initially As Required
25 to 35 ug/kg (30 (30)) As recommended. Intra Venous — Initially As Required
3 to 4.5 ug/kg (3.8 (3.75)) 12 hourly Intra Muscular — Maintenance (25% of loading dose)
3 to 4.5 ug/kg (3.8 (3.75)) 12 hourly Intra Venous — Maintenance (25% of loading dose)
3.75 to 5 ug/kg (4.4 (4.375)) 12 hourly Oral — Maintenance (25% of loading dose)
30 to 40 ug/kg (35 (35)) As recommended. Oral — Initially, As Required
Neonatal Dosage
35 to 60 ug/kg (48 (47.5)) As recommended. oral — Initial dose, As required
5 to 7.5 mg/kg (6.2 (6.25)) 12 hourly oral — Maintenance, As required
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with digoxin. This includes prescription and over-the-counter medicines, vitamins , and herbal products . Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Store in a well closed container, Between 15°C-25°C. Protect from Sunlight. Inj Store Below 40°C. Do not Freeze. Tab, Syrup Store in a well closed container, Below 40°C.
Available Brands in Pakistan
5 active brands listed alphabetically.
DIGITEK
ActiveGLOBAL BRANDS DISTRIBUTORS
DML: DIGITEK
Tabs
DIGOX
ActivePLATINUM PHARMACEUTICALS (PVT.) LTD.
DML: DIGOX
Tabs
DIGOXIN
ActiveGLOBAL BRANDS DISTRIBUTORS
DML: DIGOXIN
Tabs
LANOXIN
ActiveGLAXOSMITHKLINE
DML: LANOXIN
InjTabs
MAXIN
ActiveSEARLE PAKISTAN (PVT.) LTD.
DML: MAXIN
Syr
1 additional record is present but flagged "Unverified / Legacy" and not listed.
