Dihydroergotamine (Mesylate)
Generic medicine reference
Not yet clinically reviewed
This entry was migrated from the earlier Pharmapedia app bundle and has not been reviewed by a named clinician on this site. It is provided for educational reference only — verify dosage and safety information against current, authoritative sources and a qualified healthcare professional before any clinical use.
Overview
Dihydroergotamine is an ergot alkaloid medicine that is used to treat a migraine or cluster headache attack. dihydroergotamine will not prevent headaches or reduce the number of attacks.
This medicine is not for common tension headaches or daily use.
Dihydroergotamine injection may also be used for purposes not listed in this medication guide.
Indications
Dihydroergotamine is an ergot alkaloid medicine that is used to treat a migraine or cluster headache attack. dihydroergotamine will not prevent headaches or reduce the number of attacks.
This medicine is not for common tension headaches or daily use.
Dihydroergotamine injection may also be used for purposes not listed in this medication guide.
Contraindications
You should not use dihydroergotamine if you are allergic to it or similar medicines (ergotamine, ergonovine, methylergonovine , and others), or if you have:
heart disease , chest pain (angina), coronary artery disease , a history of a heart attack or stroke; circulation problems such as peripheral vascular disease ; uncontrolled high blood pressure ; sepsis (a severe reaction to an infection). severe liver or kidney disease; if you are allergic to dihydroergotamine or other ergot medicine (ergonovine, ergotamine, methylergonovine); or if you have had vascular surgery .
Some drugs should not be used with dihydroergotamine. Your treatment plan may change if you also use:
an antibiotic such as clarithromycin or erythromycin ; antifungal medicine such as itraconazole or ketoconazole ; or antiviral medicine for HIV or hepatitis C .
Tell your doctor if you have ever had:
blood circulation problems in your arms, hands, legs, or feet; chest pain, shortness of breath; liver or kidney disease; or risk factors for coronary artery disease (high blood pressure, high cholesterol , diabetes, menopause, smoking, family history of coronary artery disease, being overweight, being over 40 and a man).
Dihydroergotamine can affect blood circulation to your uterus. Tell your doctor if you are pregnant or plan to become pregnant. Do not use dihydroergotamine if you are pregnant.
Do not breastfeed while using this medicine, and for at least 3 days after your last dose. Talk with your doctor about the best way to feed your baby.
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Dihydroergotamine may cause serious side effects. Call your doctor at once if you have:
signs of a blood clot --sudden numbness or weakness on one side of the body, problems with vision or speech, pain or swelling in one leg; numbness or tingling in your fingers or toes; muscle pain in your arms or legs; leg weakness; fast or slow heartbeats; chest pain or tightness, shortness of breath ; swelling or itching; stomach cramps, diarrhea that may be bloody; severe headache; or discoloration or skin changes in your hands or feet.
Common side effects of dihydroergotamine may include:
headache, dizziness, anxiety; diarrhea; numbness, tingling, burning pain; increased blood pressure; rash, increased sweating; or flushing (sudden warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Tell your doctor about all your other medicines. Some drugs should not be used with dihydroergotamine.
High Risk Groups
Tell your doctor about all your other medicines. Some drugs should not be used with dihydroergotamine.
Adult Dosage
0.014 mg/kg (0.014 (0.014)) As recommended. IM — Maint, As Req, after 30-60 Min of the Initial Dose
0.014 mg/kg (0.014 (0.014)) As recommended. SC — Maint, As Req, after 30-60 Min of the Initial Dose
0.014 to 0.029 mg/kg (0.021 (0.0215)) As recommended. IM — Initially for Once
0.014 to 0.029 mg/kg (0.021 (0.0215)) As recommended. SC — Initially for Once
Child Dosage
No child dosage information is recorded for this medicine yet.
Neonatal Dosage
No neonatal dosage information is recorded for this medicine yet.
Drug Interactions
Tell your doctor about all your current medicines. Many drugs can affect dihydroergotamine, especially:
heart or blood pressure medication; nicotine gum or patches; an antidepressant; or medicine to treat an infection.
This list is not complete. Many drugs can affect dihydroergotamine. This includes prescription and over-the-counter medicines, vitamins, and herbal products . Not all possible interactions are listed here. Tell your doctor about all other medicines you use.
Storage
Aerosol Store at room temperature, Below 25°C. Refrigeration and Freezing is not recommended. Protect from Sunlight and Moisture.
Available Brands in Pakistan
No brands are recorded for this generic.